Randomized trial of surgery versus radiotherapy in patients with stage IIIA (N2) non small-cell lung cancer after a response to induction chemotherapy. EORTC 08941.

Randomized trial of surgery versus radiotherapy in patients with stage IIIA (N2) non small-cell lung cancer after a response to induction chemotherapy. EORTC 08941.
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对诱导化疗有反应的 IIIA (N2) 期非小细胞肺癌患者进行手术与放疗的随机试验。

DOI:
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发表时间:
2000
影响因子:
3.6
通讯作者:
A. Kirkpatrick
A. Kirkpatrick
中科院分区:
医学3区
文献类型:
--
作者:
T. Splinter;P. V. Van Schil;G. Kramer;J. V. van Meerbeeck;A. Gregor;P. Rocmans;A. Kirkpatrick

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III期非小细胞肺癌(NSCLC)患者的综合治疗最近已被广泛接受。标准组合是新辅助化疗后放疗或同步化疗和放疗。综合治疗对生存的影响取决于化疗根除微转移的功效和最佳局部控制。欧洲癌症研究和治疗组织(EORTC)肺癌合作组选择以比较的方式研究放射治疗与手术治疗IIIA期(N2)NSCLC的副作用和对生存期的影响。
Combined modality treatment of patients with stage III non small-cell lung cancer (NSCLC) has recently become widely accepted. Standard combinations are neoadjuvant chemotherapy followed by radiotherapy or concurrent chemotherapy and radiotherapy. The effect of combined modality treatment on survival is dependent on both the efficacy of chemotherapy to eradicate micrometastases and optimal local control. The European Organization for Research and Treatment of Cancer (EORTC) Lung Cancer Cooperative Group has chosen to investigate in a comparative way the side effects and the effect on survival of radiotherapy versus surgery in stage IIIA (N2) NSCLC.
DOI: 10.1200/jco.1995.13.8.1880
发表时间: 1995-08-01
影响因子: 45.3
作者:
ALBAIN, KS;RUSCH, VW;LIVINGSTON, RB
通讯作者: LIVINGSTON, RB
DOI: 10.1056/nejm199202203260805
发表时间: 1992-02-20
影响因子: 158.5
作者:
SCHAAKEKONING, C;VANDENBOGAERT, W;BARTELINK, H
通讯作者: BARTELINK, H