The synthesis of chitosan-based silver nanoparticles and their antibacterial activity
The synthesis of chitosan-based silver nanoparticles and their antibacterial activity
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DOI：
10.1016/j.carres.2009.09.001
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发表时间：
2009-11-23
影响因子：
3.1
通讯作者：
Ma, Xiaoyuan
中科院分区：
文献类型：
--
作者：
Wei, Dongwei;Sun, Wuyong;Ma, Xiaoyuan
用无毒、可生物降解的壳聚糖还原硝酸银盐，制备了壳聚糖基纳米银。由此得到的银纳米颗粒对革兰氏阳性和革兰氏阴性细菌都显示出很强的抗菌活性，与高活性的前体银盐相当。以硝酸银和壳聚糖为原料，经热处理，制得浸银壳聚糖膜。与纯壳聚糖膜相比，含银壳聚糖膜对大肠杆菌具有快速、持久的抗菌效果。在本系统中制备的银系抗菌材料具有广泛的生物医学和一般应用前景。(C)2009爱思唯尔有限公司。保留所有权利。
Chitosan-based silver nanoparticles were synthesized by reducing silver nitrate salts with nontoxic and biodegradable chitosan. The silver nanoparticles thus obtained showed highly potent antibacterial activity toward both Gram-positive and Gram-negative bacteria, comparable with the highly active precursor silver salts. Silver-impregnated chitosan films were formed from the starting materials composed of silver nitrate and chitosan via thermal treatment. Compared with pure chitosan films, chitosan films with silver showed both fast and long-lasting antibacterial effectiveness against Escherichia coli. The silver antibacterial materials prepared in our present system are promising candidates for a wide range of biomedical and general applications. (C) 2009 Elsevier Ltd. All rights reserved.