Cryoablation for Secondary Renal Cell Carcinoma After Surgical Nephrectomy
Cryoablation for Secondary Renal Cell Carcinoma After Surgical Nephrectomy
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肾切除术后继发性肾细胞癌的冷冻消融
DOI：
10.1007/s00270-020-02709-w
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发表时间：
2020
影响因子：
2.9
通讯作者：
Ishigami Kousei
中科院分区：
文献类型：
--
作者：
Ushijima Yasuhiro;Asayama Yoshiki;Nishie Akihiro;Takayama Yukihisa;Kubo Yuichiro;Ishimatsu Keisuke;Ishigami Kousei
目的回顾性评价冷冻消融术治疗继发性肾癌的临床结果，对于有原发性肾癌肾切除术史的患者，材料和方法2014年4月至2018年12月期间，在单中心接受原发性肾癌肾切除术和肾细胞癌冷冻消融术作为继发性治疗的30例患者，40个肾肿瘤机构已注册。评价患者的总生存率、局部控制率、无复发生存率、肾功能变化和并发症。结果全组5年总生存率为94. 5%，5年局部控制率为89. 3%，5年无复发生存率（RFSR）为5 6. 3%。1年后肾功能平均下降8.5%，仅1例发生> 3级并发症。初发T3期患者的RFSR为0%，明显低于初发T1或T2期患者的70.4%RFSR。结论肾切除术后继发性肾癌行冷冻治疗安全，局部控制好，肾功能保留。然而，对于T3期初发肾细胞癌患者，冷冻消融术的适应证应慎重考虑，因为复发风险较高。证据等级III
PurposeTo retrospectively evaluate the clinical outcomes of cryoablation for secondary renal cell carcinoma for patients with a history of nephrectomy for initial renal cell carcinoma.Materials and MethodsThirty patients with 40 renal tumors who had undergone a nephrectomy for initial renal cell carcinoma and cryoablation for renal cell carcinoma as a secondary treatment during the period from April 2014 to December 2018 at a single center institution were enrolled. The patients' overall survival, local control, relapse-free survival, change of renal function, and complications were evaluated. The clinical factors of relapse-free survival were also evaluated.ResultsThe 5 year overall survival rate was 94.5%, the 5 year local control rate was 89.3%, and the 5 year relapse-free survival rate (RFSR) was 56.3%. There was an average reduction in renal function of 8.5% after 1 year, and > grade 3 complications occurred in only one case. The RFSR in the patients whose initial stage was T3 was 0%, significantly lower than the 70.4% RFSR in the patients whose initial stage was T1 or T2.ConclusionCryoablation for secondary renal cell carcinoma after nephrectomy was safe and provided good local control with preserved renal function. However, the indications for cryoablation should be carefully considered for patients with T3-stage initial renal cell carcinoma, because of the high risk of relapse.Level of evidenceIII
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经皮图像引导热消融治疗多灶性肾细胞癌：单中心 10 年经验。
DOI：
10.2214/ajr.17.18290
发表时间：
2017
期刊：
AJR. American journal of roentgenology
影响因子：
--
作者：
Wenhui Zhou;R. Uppot;A. Feldman;R. Arellano
通讯作者：
R. Arellano
DOI：
10.1016/j.jvir.2011.09.002
发表时间：
2012-01-01
影响因子：
2.9
作者：
Wehrenberg-Klee, Eric;Clark, Timothy W. I.;Stavropoulos, S. William
通讯作者：
Stavropoulos, S. William
同侧肾脏的多个肿瘤切除会增加部分肾切除术后的并发症。
影响因子：
2.7
作者：
M. Maurice;D. Ramirez;R. Nelson;Peter A. Caputo;Ö. Kara;E. Malkoç;J. Kaouk
通讯作者：
J. Kaouk
经皮冷冻消融治疗经活检证实的 pT1NxMx 肾细胞癌的安全性和有效性的前瞻性分析
影响因子：
2.9
作者：
R. Rodriguez;Z. Cizman;K. Hong;Alexandra Koliatsos;C. Georgiades
通讯作者：
C. Georgiades
影响因子：
5
作者：
Weisbrod, Adam J.;Atwell, Thomas D.;Charboneau, J. William
通讯作者：
Charboneau, J. William