AALAS/FELASA Working Group on Health Monitoring of rodents for animal transfer.
AALAS/FELASA Working Group on Health Monitoring of rodents for animal transfer.
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AALAS/FELASA 动物转移啮齿动物健康监测工作组。
DOI：
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发表时间：
2014
影响因子：
1.7
通讯作者：
L. Riley
中科院分区：
文献类型：
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作者：
K. Pritchett;J. Prins;R. Feinstein;J. Goodwin;W. Nicklas;L. Riley
随着转基因啮齿动物的兴起，世界各地的动物运输量也相应增加。尽管对冷冻保存的啮齿动物种质的运输限制较少，但并非所有机构都有能力轻松地从所需的小鼠中产生种质，或将种质重组为活体动物。因此，活的啮齿动物仍在国际上移动，这需要密切关注动物卫生和动物卫生报告。在某些情况下，区域组织提出了最低限度可接受的健康监测方案和报告格式7。机构健康监测结果的报告仍然差别很大，但是，FELASA国家的经验表明，关于共同报告格式的建议可能导致更统一的报告。报告的差异不仅造成了不确定性，而且增加了严格审查结果所需的时间，并增加了作为运输过程一部分的机构之间沟通的总体数量，这两者都减缓了收购过程。此外，缺乏报告标准可能导致错过关键信息，这可能导致向设施引入不需要的代理。最近，FELASA对健康监测建议进行了修订，现在可以免费获得与此同时，由FELASA和AALAS成立的一个联合工作组评估了用于国际转移的共同健康报告的可能性。这份拟议的健康报告比FELASA健康监测工作组建议的报告更详细，但包含了该工作组所做的更改。
The rise of the genetically modified rodent has seen the corresponding rise of shipments of animals around the world. Although there are fewer restrictions on shipment of cryopreserved rodent germplasm, not all institutions have the capacity to either easily generate germplasm from desired mice or to reconstitute germplasm into live animals. Thus, live rodents are still moved internationally and this has necessitated close attention to animal health and animal health reporting. In some cases, regional organizations have suggested minimally acceptable health monitoring (HM) programs as well as reporting formats 7. The reporting of institutional health monitoring results remains wildly disparate, however, experience from FELASA countries shows that recommendations on a common reporting format may lead to more uniform reporting. Disparity in reporting not only creates uncertainty, but increases the time necessary to critically review results as well as increasing the overall number of communications between institutions as part of the shipping process, both of which slow the acquisition process. In addition, the lack of a reporting standard can lead to critical information being missed, which may result in the introduction of an unwanted agent to a facility. Recently, the FELASA health monitoring recommendations have been revised and are now freely available.4 In the meantime, a joint working group established by of FELASA and AALAS has evaluated the potential for a common health report to be used for international transfer. This proposed health report is more detailed than that suggested by the FELASA Working Group on Health Monitoring, but is inclusive of the changes that group made.