The synthesis, self-assembly and pH-responsive fluorescence enhancement of an alternating amphiphilic copolymer with azobenzene pendants
The synthesis, self-assembly and pH-responsive fluorescence enhancement of an alternating amphiphilic copolymer with azobenzene pendants
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偶氮苯交替两亲共聚物的合成、自组装和 pH 响应荧光增强
DOI：
10.1039/c9py00634f
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发表时间：
2019
影响因子：
4.6
通讯作者：
Lin Shaoliang
中科院分区：
文献类型：
--
作者：
Wu Jiacheng;Xu Binbin;Liu Zhenghui;Yao Yuan;Zhuang Qixin;Lin Shaoliang
本文通过叠氮-炔点击反应合成了一种新型的偶氮苯侧基交替两亲共聚物（AAC）P（EG 4-a-NAzoOMe）。该AAC通过利用特殊的交替两亲拓扑结构来防止偶氮苯侧基有序聚集，从而表现出不寻常的光响应和pH响应行为。P（EG 4-a-NAzoOMe）可以通过调节初始浓度自组装成不同大小的均质大胶束。LCMs对UV刺激的响应几乎与P（EG 4-a-NAzoOMe）聚合物一样快，并且LCMs的尺寸随着溶液的酸度而增大，颜色从黄色变为紫色。此外，由于特殊的交替两亲性拓扑结构，LCMs具有类似的酸性增强聚集诱导发射（AIE）。首次报道的刺激响应型AAC不仅可以作为一种有前途的可调谐传递载体或传感器，而且对开发偶氮苯AIE材料具有启发意义。
In this work, a novel alternating amphiphilic copolymer (AAC) P(EG4-a-NAzoOMe) with azobenzene pendants was synthesized through the azide–alkyne click reaction. This proposed AAC exhibits unusual photo- and pH-responsive behaviors by taking advantage of a special alternating amphiphilic topology to prevent the azobenzene pendants from ordered aggregation. P(EG4-a-NAzoOMe) could self-assemble into different sized homogeneous large compound micelles (LCMs) by tuning the initial concentration. The LCMs responded to UV stimuli almost as fast as the P(EG4-a-NAzoOMe) polymer, and the size of LCMs enlarged with the acidity of the solution together with the color change from yellow to violet. Moreover, the LCMs featured acidity-enhanced aggregation induced emission (AIE) similarly because of the special alternating amphiphilic topology. The first reported stimuli-responsive AAC could not only serve as a promising tunable delivery carrier or sensor, but also be inspirational for developing azobenzene AIE materials.