Acceptability of a COVID-19 vaccine among adults in the United States: How many people would get vaccinated?
Acceptability of a COVID-19 vaccine among adults in the United States: How many people would get vaccinated?
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DOI：
10.1016/j.vaccine.2020.08.043
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发表时间：
2020-09-29
期刊：
影响因子：
5.5
通讯作者：
Katz, Mira L.
中科院分区：
文献类型：
--
作者：
Reiter, Paul L.;Pennell, Michael L.;Katz, Mira L.
背景：2019冠状病毒病（COVID-19）于二零二零年三月被宣布为大流行。目前正在开发几种针对COVID-19的预防性疫苗，但人们对COVID-19疫苗的可接受性知之甚少。方法：我们于2020年5月对美国18岁及以上的成年人（n = 2，006）进行了一项在线调查。多变量相对风险回归确定了参与者接种COVID-19疫苗意愿的相关性（即，结果：总体而言，69%的参与者愿意接种COVID-19疫苗。如果参与者认为他们的医疗保健提供者会建议接种疫苗（RR = 1.73，95% CI：1.49-2.02），或者如果他们的政治倾向是温和的（RR = 1.09，95% CI：1.02-1.16）或自由的（RR = 1.14，95% CI：1.07-1.22），他们更有可能愿意接种疫苗。如果参与者报告未来感染COVID-19的可能性更高，他们也更愿意接种疫苗（RR = 1.05，95% CI：1.01-1.09），COVID-19感染的感知严重程度（RR = 1.08，95%CI：1.04-1.11）或COVID-19疫苗的感知有效性（RR = 1.46，95%CI：1.40-1.52）。参与者不太可能愿意接种疫苗，如果他们是非拉丁裔黑人（RR = 0.81，95% CI：0.74-0.90）或报告了更高水平的感知潜在疫苗危害（RR = 0.95，95%CI：0.92-0.98）。许多成年人愿意接种COVID-19疫苗，但随着疫苗开发的继续，应监测可接受性。我们的研究结果可以帮助指导未来提高COVID-19疫苗可接受性（以及疫苗可用时的吸收）的努力。(C)2020爱思唯尔有限公司保留所有权利。
Background: Coronavirus disease 2019 (COVID-19) was declared a pandemic in March 2020. Several prophylactic vaccines against COVID-19 are currently in development, yet little is known about people's acceptability of a COVID-19 vaccine.Methods: We conducted an online survey of adults ages 18 and older in the United States (n = 2,006) in May 2020. Multivariable relative risk regression identified correlates of participants' willingness to get a COVID-19 vaccine (i.e., vaccine acceptability).Results: Overall, 69% of participants were willing to get a COVID-19 vaccine. Participants were more likely to be willing to get vaccinated if they thought their healthcare provider would recommend vaccination (RR = 1.73, 95% CI: 1.49-2.02) or if they were moderate (RR = 1.09, 95% CI: 1.02-1.16) or liberal (RR = 1.14, 95% CI: 1.07-1.22) in their political leaning. Participants were also more likely to be willing to get vaccinated if they reported higher levels of perceived likelihood getting a COVID-19 infection in the future (RR = 1.05, 95% CI: 1.01-1.09), perceived severity of COVID-19 infection (RR = 1.08, 95% CI: 1.04-1.11), or perceived effectiveness of a COVID-19 vaccine (RR = 1.46, 95% CI: 1.40-1.52). Participants were less likely to be willing to get vaccinated if they were non-Latinx black (RR = 0.81, 95% CI: 0.74-0.90) or reported a higher level of perceived potential vaccine harms (RR = 0.95, 95% CI: 0.92-0.98).Conclusions: Many adults are willing to get a COVID-19 vaccine, though acceptability should be monitored as vaccine development continues. Our findings can help guide future efforts to increase COVID-19 vaccine acceptability (and uptake if a vaccine becomes available). (C) 2020 Elsevier Ltd. All rights reserved.