Regulation of Renin Release

Regulation of Renin Release
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肾素释放调节

DOI:
10.1007/978-3-642-61164-3_5
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发表时间:
1996
期刊:
--
影响因子:
--
通讯作者:
Y. Takei
Y. Takei
中科院分区:
--
文献类型:
--
作者:
Hideshi Kobayashi;Y. Takei

文献摘要

被引文献

相似文献

尽管对哺乳动物中调节肾素释放的机制进行了大量的研究,但在非哺乳动物物种中的研究相当缺乏。因此,本章的第一部分将致力于审查目前的知识状态有关的调节,在哺乳动物的肾素释放。Davis和Freeman(1976年)、Keeton和坎贝尔(1981年)、Gibbons等人(1984年)、Fray等人(1987年)和Hackenthal等人(1990年)对该机制的细节进行了广泛的综述。越来越多的证据表明,肾脏分泌活性和非活性的肾素,并且非活性的肾素的活化显著地有助于人(Sealey和Laragh 1975)、狗(James和Hall 1974)和猪(Bailie等人1979; Okamura和Inagami 1984)的血浆肾素活性的变化。然而,这种激活过程在非哺乳动物物种中尚未得到充分研究。
Despite an abundance of studies on the mechanisms regulating renin release in mammals, studies in nonmammalian species are rather scant. The initial part of this chapter will therefore be devoted to reviewing the present state of knowledge about the regulation of renin release in mammals. The details of the mechanism are extensively reviewed by Davis and Freeman (1976), Keeton and Campbell (1981), Gibbons et al. (1984), Fray et al. (1987) and Hackenthal et al. (1990). Increasing evidence shows that the kidney secretes both active and inactive renin, and the activation of inactive renin signiIicantly contributes to changes in plasma renin activity in humans (Sealey and Laragh 1975), dogs (James and Hall 1974), and pigs (Bailie et al. 1979; Okamura and Inagami 1984). This activation process, however, has not been studied sufficiently in nonmammalian species.