Three infants with rotavirus gastroenteritis complicated by severe gastrointestinal bleeding.
Three infants with rotavirus gastroenteritis complicated by severe gastrointestinal bleeding.
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3例婴儿轮状病毒胃肠炎并发严重消化道出血。
DOI：
10.1002/jmv.24297
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发表时间：
2016
期刊：
影响因子：
12.7
通讯作者：
Yoshikawa T.
中科院分区：
文献类型：
--
作者：
Kawamura Y;Miura H;Mori Y;Sugata K;Nakajima Y;Morooka M;Tsuge I;Taniguchi K;Yoshikawa T.
轮状病毒胃肠炎在全球范围内引起儿童的大量发病率和死亡率。我们报告三个婴幼儿轮状病毒肠胃炎并发不同程度的消化道出血。2例患者（病例1和2）在未接受任何特殊治疗的情况下完全恢复。1例患者（病例3）尽管接受了广泛治疗（包括红细胞输注和内镜止血治疗），但仍死亡。在病例2和病例3中分别检测到轮状病毒基因型G1 P [8]和G9 P [8]。轮状病毒抗原血症水平在黑便发病时并不高，表明全身轮状病毒感染在引起黑便中并不起重要作用。88：171-174，2016.© 2015 Wiley Periodicals，Inc.
Rotavirus gastroenteritis causes substantial morbidity and mortality worldwide in children. We report three infants with rotavirus gastroenteritis complicated by various severity of gastrointestinal bleeding. Two patients (cases 1 and 2) recovered completely without any specific treatments. One patient (case 3) died despite extensive treatments including a red blood cell transfusion and endoscopic hemostatic therapy. Rotavirus genotypes G1P[8] and G9P[8] were detected in cases 2 and 3, respectively. Rotavirus antigenemia levels were not high at the onset of melena, suggesting that systemic rotaviral infection does not play an important role in causing melena.J. Med. Virol. 88:171–174, 2016.© 2015 Wiley Periodicals, Inc.