PGI2 Is a Novel SGI1-Relative Multidrug-Resistant Genomic Island Characterized in Proteus mirabilis

PGI2 Is a Novel SGI1-Relative Multidrug-Resistant Genomic Island Characterized in Proteus mirabilis
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PGI2 是一种新型 SGI1 相关多重耐药基因组岛,以奇异变形杆菌为特征

DOI:
10.1128/aac.00019-18
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发表时间:
2018-05-01
影响因子:
4.9
通讯作者:
Wang, Hong-Ning
Wang, Hong-Ning
中科院分区:
医学2区
文献类型:
--
作者:
Lei, Chang-Wei;Chen, Yan-Peng;Wang, Hong-Ning

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ABSTRACT A novel 61,578-bp genomic island named Proteus genomic island 2 (PGI2) was characterized in Proteus mirabilis of swine origin in China. The 23.85-kb backbone of PGI2 is related to those of Salmonella genomic island 1 and Acinetobacter genomic island 1. The multidrug resistance (MDR) region of PGI2 is a complex class 1 integron containing 14 different resistance genes. PGI2 was conjugally mobilized in trans to Escherichia coli in the presence of a conjugative IncC helper plasmid.