The effect of celery (Apium graveolens L.) on fertility: A systematic review.
The effect of celery (Apium graveolens L.) on fertility: A systematic review.
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DOI：
10.1515/jcim-2016-0141
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发表时间：
2017-10-06
影响因子：
--
通讯作者：
Ghafourian, Mehri
中科院分区：
文献类型：
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作者：
Kooti, Wesam;Moradi, Maryam;Ghafourian, Mehri
背景生育和不育问题是医学中的复杂问题之一。使用草药产品治疗生育能力已被认为是合成药物的替代品。芹菜含有已知的化合物可以对生育率产生影响。本研究的目的是做一个系统的回顾，进行研究，结合芹菜和繁殖。方法检索Science Direct、PubMed、Scopus、Springer等数据库。本研究采用的关键词为“芹菜”。“、“生育力”、“生殖系统”、“精子”、“睾丸”、“分娩”、“性激素”、“LH”、“FSH”、“睾酮”、“精液”、“雄性”和“雌性”。在收集的238篇文章（1995年至2015年期间发表）中，有222篇由于不相关和无法访问原始文章而被排除。结果值得注意的是不同研究者在不同治疗时期或不同剂量下观察到的结果不同。在这项研究中回顾的16项研究中，有13项研究提到了芹菜对生育的积极影响，而三项研究报告了这种植物的抑制作用。结论芹菜对丙戊酸钠、丙二醇、邻苯二甲酸二乙酯等物质引起的睾丸结构损伤和精子发生具有保护作用。在这方面，必须准确调查使用植物时所用的剂量和处理时间。由于芹菜中含有芹菜素等化合物，长期使用或高浓度使用芹菜会对生育能力产生抑制作用。
Background Fertility and infertility problems are among the complex issues in medicine. The use of herbal products in the treatment of fertility has been considered as an alternative to synthetic drugs. Celery containing known compounds can have an impact on the fertility rate. The aim of this study was to do a systematic review on conducted studies in conjunction with the celery and reproduction. Methods Required papers were searched from databases like Science direct, PubMed, Scopus, and Springer. Keywords used in this study were "Apium graveolens L.", "fertility", "reproductive system", "sperm", "testis", "delivery", "sexual hormone", "LH", "FSH", "testosterone", "semen", "male", and "female". Out of 238 collected articles (published in the period 1995 to 2015), 222 were excluded due to non-relevance and lack of access to the original article. Results The notable points were the different results seen by different researchers during different treatment periods or at different doses. Of the 16 studies reviewed in this study, 13 studies have mentioned the positive effect of celery on fertility, while three studies reported the inhibitory effects of this plant. Conclusions Celery can have protective effects against substances such as sodium valproate, propylene glycol, and diethyl phthalate causing damages to the testicular structure and spermatogenesis. In this regard, the doses used and the treatment time while using the plant must be accurately investigated. Since there are compounds such as apigenin, the celery can induce inhibitory effects on fertility in case of chronic use or high concentration.