THE INFLUENCE OF AGE ON SOME OCULAR BASEMENT-MEMBRANES
THE INFLUENCE OF AGE ON SOME OCULAR BASEMENT-MEMBRANES
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DOI：
10.1038/eye.1987.35
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发表时间：
1987-01-01
期刊：
影响因子：
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通讯作者：
FISHER, RF
中科院分区：
文献类型：
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作者：
FISHER, RF
本文测定了人晶状体囊膜和膜的杨氏S弹性模数随年龄的变化。晶状体囊膜的弹性系数随年龄增长而减小，而S膜的弹性系数随年龄的增长而增大。还测定了人晶状体囊膜和Bruch‘S膜的水力传导性随年龄的变化，并再次显示了相反的变化。前者的渗透系数增大，而后者的渗透系数减小。膜的老化变化表明，在人类中，在所有情况下，100年后的某个时间，晶状体囊膜将具有与晚期白内障晶状体相似的水力传导性，而在同一对象中，S膜将失去对水的渗透性。
Changes with age in the Young''s modulus of elasticity of human lens capsule and Bruch''s membrane have been determined. In lens capsule the modulus decreases with age whereas in Bruch''s membrane it increases. Changes with age in the hydraulic conductivity of the human lens capsule and Bruch''s membrane have also been determined and again show opposite changes with age. In the former membrane the hydraulic conductivity increases while in the latter it decreases. The ageing changes in the respective membranes indicate that, in man, some time after 100 years in all cases the lens capsule would have a similar hydraulic conductivity to lenses with advanced cataract, while in the same subject Bruch''s membrane would have lost its permeability to water.