Physical-Chemical Aggressiveness of Solutions of Medicines as a Factor in the Rheology of the Blood inside Veins and Catheters
Physical-Chemical Aggressiveness of Solutions of Medicines as a Factor in the Rheology of the Blood inside Veins and Catheters
复制标题
药物溶液的物理化学侵蚀性作为静脉和导管内血液流变学的一个因素
DOI：
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发表时间：
2014
期刊：
影响因子：
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通讯作者：
Chernova
中科院分区：
文献类型：
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作者：
Aleksandr;Urakov;Natalia;Urakova;Anton;Kasatkin;Leisan;Chernova
在体外实验和体内临床观察中，根据药物溶液的温度、体积、浓度、渗透活性和ph值，研究了患者与血管导管和药物溶液相互作用后皮下静脉腔的状态和血液流变学。结果表明，血液中注射肝素不能预防血液凝固，但4%碳酸氢钠注射液可以预防静脉和导管的血栓、血栓和堵塞血栓。结果表明，用4%碳酸氢钠溶液加热到+42°С的温度可以在1分钟内软化旧的干血凝块，随后用4%碳酸氢钠和3%过氧化氢的温溶液冲洗，可以在2秒内完全破坏和变色剩余的血液斑点。提出了新的药物和卫生用品，用于保护静脉，并在静脉中安装血管导管，防止血栓堵塞，并用于清除患者衣服和体表的血迹。
In experiments in vitro and observations in the clinic in vivo studied the state of the lumen of subcutaneous veins and blood rheology of patients after their interaction with vascular catheters and solutions of medicines based on the values of temperature, volume, concentration, osmotic activity and pH. It is shown that heparin injection in blood not prevent, but solution of 4% sodium bicarbonate injection prevents blood clotting, blood clots and blockage blood clots of veins and of catheters. It is shown that the heating to a temperature of +42 °С with the solution of 4% sodium bicarbonate provides softening action on old dry blood clots in 1 min, and their subsequent irrigation with a warm solution of 4% sodium bicarbonate and 3% hydrogen peroxide provides complete destruction and discoloration of the remaining spots of blood during 2 s. Proposed new medicines and hygiene products for the protection of the veins and installed in them vascular catheters from blockage of blood clots, and for removing blood stains from clothes and body surface patients.