Epidemiology of meningitis in Al-Ain, United Arab Emirates, 2000-2005
Epidemiology of meningitis in Al-Ain, United Arab Emirates, 2000-2005
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DOI：
10.1016/j.ijid.2006.05.009
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发表时间：
2007-07-01
影响因子：
8.4
通讯作者：
Smego, Raymond A., Jr.
中科院分区：
文献类型：
--
作者：
Dash, Nihar;Ameen, Abdulmajeed S.;Smego, Raymond A., Jr.
目的：描述阿拉伯联合酋长国 At-Ain 医疗区 2000 年 1 月至 2005 年 6 月期间脑膜炎的流行病学特征。方法：对向 AI.-Ain 预防医学部报告的脑膜炎病例的临床记录和通知表进行回顾性审查。收集和整理的数据包括人口特征、致病微生物以及按病因分类的脑膜炎年发病率。结果：在研究期间报告了 92 例脑膜炎病例； 53% 是细菌性的，37% 是病毒性的。脑膜炎奈瑟菌是主要的细菌病原体（35%），其次是肺炎链球菌（16%）。临床诊断的脑膜炎病例中，有 10% 没有发现致病微生物，而在 33% 的推测化脓性脑膜炎患者中，没有发现特定的细菌病原体。脑膜炎的发病高峰是一岁以内的幼儿。脑膜炎球菌性脑膜炎病例多见于监狱囚犯和劳工，白病毒性脑膜炎主要发生在上学的儿童和青壮年。 At-Ain市脑膜炎发病率从2000年的2.2/10万人口到2005年的1/10万人口，总体呈逐年下降趋势。 1999年实施国家免疫规划后，b型流感嗜血杆菌发病率显着下降。结论：必须改进细菌检测方法，包括分离株血清分型，以进一步降低脑膜炎的死亡率和发病率。 (C) 2006 年国际传染病学会。由爱思唯尔有限公司出版。保留所有权利。
Objective: To describe the epidemiologic features of meningitis in At-Ain Medical District, United Arab Emirates from January 2000 through June 2005.Methods: A retrospective review of clinical records and notification forms for cases of meningitis reported to the Department of Preventive Medicine, AI.-Ain. Data collected and compiled included demographic features, causative microbiologic agents, and annual incidence rates of meningitis, by etiology.Results: Ninety-two cases of meningitis were reported during the study period; 53% were bacterial and 37% were viral in origin. Neisseria meningitidis was the leading bacterial, pathogen (35%) followed by Streptococcus pneumoniae (16%). Ten percent of clinically diagnosed cases of meningitis had no causative microorganism recovered, and in 33% of patients with presumed pyogenic meningitis no specific bacterial pathogen could be identified. The peak occurrence of meningitis was in young children Less than one year old. Most cases of meningococcal meningitis were seen among prison inmates and laborers, white viral meningitis occurred mainly in children and young adults attending school. The incidence rate of meningitis in At-Ain ranged between 2.2/100 000 population in 2000 and 1/100 000 in 2005, with an overall downward trend by year. The incidence of Haemophilus influenzae type b decreased significantly after implementation of the national immunization program in 1999.Conclusions: Improved methods of bacterial, detection including isolate serotyping must be made available in order to further reduce mortality and morbidity from meningitis. (C) 2006 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.