Preferential correlations of a medullary neuron's activity to different sympathetic outflows as revealed by partial coherence analysis.
Preferential correlations of a medullary neuron's activity to different sympathetic outflows as revealed by partial coherence analysis.
复制标题
部分相干分析揭示了髓质神经元活动与不同交感神经流出的优先相关性。
DOI：
10.1152/jn.1995.74.1.474
复制
发表时间：
1995
期刊：
影响因子：
--
通讯作者：
Huang,WX
中科院分区：
文献类型：
--
作者：
Cohen,MI;Yu,Q;Huang,WX
1.在迷走神经切断，瘫痪，去脑猫，同时记录从一个或多个交感神经[颈交感神经（CS），下心（IC），内脏（SP）]和从延髓神经元在血管运动相关区域。相干分析用于确定不同信号之间相关的交感神经节律（2-6 Hz或“3-Hz节律”，7-13 Hz或“10-Hz节律”）的存在。在单位神经相干谱中在这样的频率处出现显著峰允许将髓神经元鉴定为交感神经相关的。2.一个偶然的例子是一个头端腹外侧髓神经元，有显着的单位神经10 Hz的相干峰三个交感神经（CS，IC，SP），但是，所揭示的部分相干性分析，单位活动的相关性与一个神经的活动可能是部分或完全依赖于其与其他神经活动的相关性。因此，在这种情况下，在10 Hz的单位CS和单位IC相干性完全依赖于SP节律，而单位SP相干性不受CS和IC节律的显着影响。这种不对称性表明，神经元优先连接到SP产生的延髓电路。3.该实施例表明部分相干性分析作为研究延髓交感神经相关神经元和交感神经输出神经元群体之间的差分连接性的手段的强度。
1. In vagotomized, paralyzed, decerebrate cats, simultaneous recordings were taken from one or more sympathetic nerves [cervical sympathetic (CS), inferior cardiac (IC), splanchnic (SP)] and from medullary neurons in vasomotor-related regions. Coherence analyses were used to ascertain the presence of sympathetic rhythms (2-6 Hz or "3-Hz rhythm," 7-13 Hz or "10-Hz rhythm") that were correlated between different signals. The occurrence of a significant peak at such a frequency in a unit-nerve coherence spectrum allowed the identification of a medullary neuron as sympathetic related. 2. A serendipitous example is given of a rostral ventrolateral medullary neuron that had significant unit-nerve 10-Hz coherence peaks for three sympathetic nerves (CS, IC, SP); but, as revealed by partial coherence analysis, the unit activity's correlation with one nerve's activity could be partially or completely dependent on its correlation with other nerve activities. Thus in this case the unit-CS and unit-IC coherences at 10 Hz were completely dependent on the SP rhythm, whereas the unit-SP coherence was not significantly affected by the CS and IC rhythms. This asymmetry suggests that the neuron was preferentially connected to SP-generating medullary circuits. 3. This example indicates the strength of partial coherence analysis as a means of studying differential connectivity between medullary sympathetic-related neurons and sympathetic output neuron populations.