Superior lubrication mechanism in poly(vinyl alcohol) hybrid gel as artificial cartilage
Superior lubrication mechanism in poly(vinyl alcohol) hybrid gel as artificial cartilage
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DOI：
10.1177/1350650117712881
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发表时间：
2017-06
期刊：
影响因子：
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通讯作者：
T. Murakami;S. Yarimitsu;N. Sakai;K. Nakashima;Tetsuo Yamaguchi;Y. Sawae;A. Suzuki
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文献类型：
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作者：
T. Murakami;S. Yarimitsu;N. Sakai;K. Nakashima;Tetsuo Yamaguchi;Y. Sawae;A. Suzuki
近年来随着材料技术的进步，超高分子量聚乙烯用于全关节假体的耐磨性得到了提高，但在恶劣条件下的摩擦磨损问题尚未完全解决。因此，具有与天然关节软骨相似特性的人工水凝胶软骨的应用有望通过改善润滑机制来解决摩擦磨损问题，具有上级摩擦学功能。本文对四种聚乙烯醇水凝胶进行了往复运动试验，并进行了两相有限元分析。以人工软骨为材料，分别采用反复冻融法（FT法）、浇铸干燥法（CD法）和混杂法制备了FT/CD、CD/FT四种不同层状结构的聚乙烯醇（PVA）水凝胶。在椭圆形聚乙烯醇（PVA）水凝胶试件与平板玻璃在盐水溶液中的往复运动试验中，四种水凝胶表现出很大的摩擦水平：杂化（CD对FT）< CD < FT <杂化（FT对CD）。注意到混合（FT上的CD）凝胶保持极低的摩擦，并显示出最小的磨损。通过两相有限元分析评价两相润滑的有效性。通过实验和有限元分析的对比，讨论了聚乙烯醇杂化（CD on FT）凝胶中流体相在早期支撑载荷的重要性和降低间隙流体压力后的表面润滑性。
With recent progress of material technologies, the wear resistance of ultra-high molecular weight polyethylene for total joint prostheses has been improved, but under severe conditions friction and wear problems have not yet been completely solved. Therefore, the application of artificial hydrogel cartilage with similar properties to natural articular cartilage is expected to solve the friction and wear problems by improvement of lubrication mechanism with superior tribological functions. In this study, reciprocating tests of four kinds of poly(vinyl alcohol) hydrogels were carried out and the biphasic finite element analysis was conducted. As artificial cartilage specimens, four kinds of poly(vinyl alcohol) hydrogels were prepared using the repeated freeze–thawing (FT) method, the cast-drying (CD) method and the hybrid method with different layered structure as FT on CD or CD on FT. In reciprocating test of ellipsoidal poly(vinyl alcohol) hydrogel specimen against flat glass plate in saline solution, four kinds of hydrogels exhibited very different frictional levels as hybrid (CD on FT) < CD < FT < hybrid (FT on CD). It is noticed that hybrid (CD on FT) gel maintained extremely low friction and showed minimal wear. The effectiveness of biphasic lubrication was evaluated by biphasic finite element analysis. The importance of the load support by fluid phase at early stage and the surface lubricity after lowering of interstitial fluid pressure in poly(vinyl alcohol) hybrid (CD on FT) gel are discussed by comparison of experiment and finite element analysis.