Bibliometric analysis of the global research development of bone metastases in prostate cancer: A 22-year study.
Bibliometric analysis of the global research development of bone metastases in prostate cancer: A 22-year study.
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DOI：
10.3389/fonc.2022.947445
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发表时间：
2022
影响因子：
4.7
通讯作者：
Guo, Zhenghui
中科院分区：
文献类型：
--
作者：
Chen, Yongming;Tang, Chen;Shen, Zefeng;Peng, Shengmeng;Wu, Wanhua;Lei, Zhen;Zhou, Jie;Li, Lingfeng;Lai, Yiming;Huang, Hai;Guo, Zhenghui
前列腺癌（PCa）是男性中第二大诊断癌症。大多数PCA相关死亡是由转移性疾病引起的。骨转移最常见（90%）。然而，目前对PCa骨转移的治疗不是很有效。本文就前列腺癌骨转移的研究现状进行综述，重点介绍其研究热点和发展趋势。我们检索了Web of Science Core Collection数据库中1999年至2021年间发表的与PCa骨转移相关的出版物。我们使用VOSviewer、CiteSpace和一个文献计量学在线平台对国家、机构、作者、期刊、参考文献和关键词进行了文献计量学分析。本研究共纳入4，832篇相关文章。美国在该领域发表的文章最多，其次是中国和英国。德克萨斯大学MD安德森癌症中心是前列腺癌骨转移研究领域的领先机构。来自加拿大的Saad F在这方面取得了很大的成就，发表了91篇相关文章。前列腺是发表相关文章最多的杂志，Mundy GR，2002，Nat Rev Cancer是该领域引用最多的文章。此外，作者关键词的分析可以分为五个聚类：（1）PCa的诊断，（2）骨转移的机制，（3）骨转移的药物治疗，（4）骨转移的放射治疗，以及（5）PCa的治疗和预后。mCRPC是近年来PCa中最热门的话题。CT是骨转移瘤最常用的诊断方法。恩杂鲁胺和镭-223作为治疗前列腺癌骨转移的重要手段，受到广泛关注。此外，研究人员还关注肿瘤微环境和生物标志物，以探索PCa骨转移的机制和治疗靶点。
Prostate cancer (PCa) is the second most diagnosed cancer in men. Most PCa-related deaths result from metastatic disease. Metastases occur most often in the bones (90%). However, the current treatments for bone metastases in PCa are not very effective. Here we present an overview of the current research situation of bone metastases in PCa, focusing on hotspots and trends. We searched the Web of Science Core Collection database for publications related to bone metastases in PCa published between 1999 and 2021. We used VOSviewer, CiteSpace, and a bibliometric online platform to perform a bibliometric analysis of countries, institutions, authors, journals, references, and keywords. A total of 4,832 related articles were included in the present study. The USA published the most articles in the field, followed by China and England. The University of Texas MD Anderson Cancer Center is the leading institution in the research field of bone metastases in PCa. Saad F, from Canada, has made great achievements in this area by publishing 91 related articles. Prostate is the journal which published most related articles, and Mundy GR, 2002, Nat Rev Cancer, is the most cited article in this field. Furthermore, the analysis of author keywords can be divided into five clusters: (1) diagnosis of PCa, (2) mechanism of bone metastasis, (3) drug treatments of bone metastases, (4) radiotherapy of bone metastases, and (5) treatments and prognosis of PCa. mCRPC has been the hottest topic in PCa in recent years. CT is the most common diagnostic method for bone metastases. Enzalutamide and radium-223, as important treatments for bone metastases in PCa, bring about widespread attention. Furthermore, the researchers focus on the tumor microenvironment and biomarkers to explore the mechanism and the therapeutic targets of bone metastases in PCa.
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DOI：
10.3390/diagnostics11020354
发表时间：
2021-02-20
期刊：
Diagnostics (Basel, Switzerland)
影响因子：
--
作者：
Tătaru OS;Vartolomei MD;Rassweiler JJ;Virgil O;Lucarelli G;Porpiglia F;Amparore D;Manfredi M;Carrieri G;Falagario U;Terracciano D;de Cobelli O;Busetto GM;Del Giudice F;Ferro M
通讯作者：
Ferro M
影响因子：
50.5
作者：
Coleman, R.;Hadji, P.;Jordan, K.
通讯作者：
Jordan, K.
影响因子：
158.5
作者：
Scher, Howard I.;Fizazi, Karim;de Bono, Johann S.
通讯作者：
de Bono, Johann S.
影响因子：
45.3
作者：
HUSSAIN, M;WOLF, M;EISENBERGER, M
通讯作者：
EISENBERGER, M
影响因子：
10.3
作者：
Saad, F;Gleason, DM;Chen, B
通讯作者：
Chen, B