Tantalum coated on titanium dioxide nanotubes by plasma spraying enhances cytocompatibility for dental implants
Tantalum coated on titanium dioxide nanotubes by plasma spraying enhances cytocompatibility for dental implants
复制标题
通过等离子喷涂在二氧化钛纳米管上涂覆钽可增强牙种植体的细胞相容性
DOI：
10.1016/j.surfcoat.2019.125161
复制
发表时间：
2020-01-25
影响因子：
5.4
通讯作者：
Liu, Hongchen
中科院分区：
文献类型：
--
作者：
Wang, Feifan;Li, Chuanjie;Liu, Hongchen
Surface modification of titanium (Ti) is a hot topic to improve osseointegration. Specifically, the composite surface treatment could produce a synergistic effect on perfect osseointegration. In this study, tantalum (Ta) was deposited on the surface of titanium dioxide (TiO2) nanotubes by means of plasma spraying to form Ta/TiO2 nanotube composite coatings. This coating was assessed by scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD), three-dimensional contour tests and contact angle measurements. The cytocompatibility was tested in vitro with mouse embryonic osteoblast precursor (MC3T3-E1) cells. The results revealed that the Ta coating was formed on the surface of TiO2 nanotubes and possessed good surface characteristics, including roughness and hydrophilicity. In addition, the Ta/TiO2 nanotube composite coating presented good adhesion, differentiation, mineralization and osteogenesis-related gene (BMP-2, Alp, OCN and OPN) expression in vitro. These results suggest that the Ta/TiO2 nanotube composite coatings can provide a favourable application for dental implants to enhance cytocompatibility.
