Two-component signal transduction systems in eukaryotic microorganisms.
Two-component signal transduction systems in eukaryotic microorganisms.
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DOI：
10.1016/s1369-5274(98)80109-4
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发表时间：
1998-12
影响因子：
5.4
通讯作者：
William F. Loomis;A. Kuspa;G. Shaulsky
中科院分区：
文献类型：
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作者：
William F. Loomis;A. Kuspa;G. Shaulsky
保守的信号转导途径，使用磷酸化从组氨酸激酶通过中间转移蛋白（H2）的反应调节剂已被发现在各种真核微生物。这些途径中有几个与丝裂原活化蛋白激酶级联有关。这些网络控制不同的生理反应，包括cAMP水平和细胞形态发生。
Conserved signal transduction pathways that use phosphorelay from histidine kinases through an intermediate transfer protein (H2) to response regulators have been found in a variety of eukaryotic microorganisms. Several of these pathways are linked to mitogen-activated protein kinase cascades. These networks control different physiological responses including osmoregulation, cAMP levels and cellular morphogenesis.