Transmission and scanning electron microscopy of host cell entry by Toxoplasma gondii.
Transmission and scanning electron microscopy of host cell entry by Toxoplasma gondii.
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弓形虫进入宿主细胞的透射和扫描电子显微镜。
DOI：
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发表时间：
1977
影响因子：
6
通讯作者：
O. Midorikawa
中科院分区：
文献类型：
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作者：
M. Aikawa;Y. Komata;T. Asai;O. Midorikawa
用透射电镜和扫描电镜观察弓形虫速殖子进入腹腔细胞的情况。进入过程是由寄生虫用其前端接触宿主细胞开始的，在宿主细胞的质膜上产生一个小凹陷。偶尔，一小部分宿主细胞质突出并接触寄生虫的前端。圆柱形结构（直径35 nm）从寄生虫的表膜延伸到宿主细胞。这种结构似乎有助于T.刚地。随着进入过程的进行，宿主细胞的伪足包围寄生虫，最后弓形虫进入细胞内，位于通过单位膜与宿主细胞质隔开的空泡中。(Am J. Pathol 87：285-296，1977）。
Entry by tachyzoites of Toxoplasma gondii, the causative agent of toxoplasmosis, into peritoneal cells was investigated with transmission and scanning electron microscopy. The process of entry is initiated by the parasite contacting the host cell with its anterior end, creating a small depression in the plasmalemma of the host cell. Occasionally, a small portion of the host cell cytoplasm protrudes and contaccts the anterior end of the parasite. A cylindrical structure (35 nm in diameter) extends from the pellicle of the parasite to the host cell. Such structures appear to assist host cell entry by T. gondii. As the entry process progresses, pseudopods of the host cell surround theparasite and finally T gondii becomes intracellular, being located in a vacuole separated from the host cell cytoplasm by a unit membrane. (Am J. Pathol 87:285-296, 1977).