The History and Innovations of Blood Vessel Anastomosis.

The History and Innovations of Blood Vessel Anastomosis.
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DOI:
10.3390/bioengineering9020075
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发表时间:
2022-02-15
期刊:
Bioengineering (Basel, Switzerland)
影响因子:
--
通讯作者:
Sacks JM
Sacks JM
中科院分区:
其他
文献类型:
--
作者:
Moritz WR;Raman S;Pessin S;Martin C;Li X;Westman A;Sacks JM

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外科手术技术和技术经常共同进化。血管吻合术的简史上名不虚传。虽然这些外科医生开创的技术已经得到了很好的描述,但促进他们进步和他们的发明者的技术值得认可。19世纪中期,实验室显微镜的大量生产引起了人们对组织组织学的兴趣。这提高了对血管生理学和血栓形成的了解,为Carrel和Guslee报告一些第一批成功的血管吻合奠定了基础。1916年,麦克莱恩发现了肝素。24年后,戈登·默里发现,在进行端到端吻合时,它可以防止血栓形成。这些发现为人类首例肾脏移植铺平了道路。耳鼻喉科医生尼伦和霍姆格伦最先将实验室显微镜带入手术室,而雅各布森则是第一个将这些技术应用于微血管吻合的人。他在1960年的第一次成功尝试和随后显微外科工具的开发使人们对显微外科的兴趣激增,随后几十年的创新。今天,新的进展有望使微血管和血管手术对患者来说更快、更便宜、更安全。外科手术的未来将永远与其创新者的创造力和远见密不可分。
Surgical technique and technology frequently coevolve. The brief history of blood vessel anastomosis is full of famous names. While the techniques pioneered by these surgeons have been well described, the technology that facilitated their advancements and their inventors deserve recognition. The mass production of laboratory microscopes in the mid-1800s allowed for an explosion of interest in tissue histology. This improved understanding of vascular physiology and thrombosis laid the groundwork for Carrel and Guthrie to report some of the first successful vascular anastomoses. In 1916, McLean discovered heparin. Twenty-four years later, Gordon Murray found that it could prevent thrombosis when performing end-to-end anastomosis. These discoveries paved the way for the first-in-human kidney transplantations. Otolaryngologists Nylen and Holmgren were the first to bring the laboratory microscope into the operating room, but Jacobson was the first to apply these techniques to microvascular anastomosis. His first successful attempt in 1960 and the subsequent development of microsurgical tools allowed for an explosion of interest in microsurgery, and several decades of innovation followed. Today, new advancements promise to make microvascular and vascular surgery faster, cheaper, and safer for patients. The future of surgery will always be inextricably tied to the creativity and vision of its innovators.
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