Fine Particulate Matter Air Pollution and Cognitive Function Among Older US Adults
Fine Particulate Matter Air Pollution and Cognitive Function Among Older US Adults
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DOI：
10.1093/aje/kwu155
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发表时间：
2014-08-15
影响因子：
5
通讯作者：
Crimmins, Eileen M.
中科院分区：
文献类型：
--
作者：
Ailshire, Jennifer A.;Crimmins, Eileen M.
关于暴露于污染对健康的不利影响的现有研究相对较少关注环境空气污染对老年人认知功能的潜在影响。我们研究了空气动力学直径为2.5 μ m或更小的颗粒物（PM2.5）的住宅浓度与老年人认知功能之间的横截面关联。使用分层线性模型，我们分析了2004年健康与退休研究的数据，这是一个大型的，具有全国代表性的50岁或以上美国成年人样本。我们将参与者数据与2000年美国人口普查区数据和2004年人口普查区水平的年平均PM2.5浓度联系起来。生活在PM2.5浓度较高地区的老年人认知功能较差（β =-0.26，95%置信区间：-0.47，-0.05），即使在调整了社区和个人水平的社会和经济特征后。结果表明，关联是最强的认知功能的情景记忆组件。这项研究增加了越来越多的研究，强调空气污染对老年人认知功能的重要性。改善大都市地区的空气质量，这是美国大部分老龄化人口居住的地方，可能是减少与年龄相关的认知能力下降的重要机制。
Existing research on the adverse health effects of exposure to pollution has devoted relatively little attention to the potential impact of ambient air pollution on cognitive function in older adults. We examined the cross-sectional association between residential concentrations of particulate matter with aerodynamic diameter of 2.5 mu m or less (PM2.5) and cognitive function in older adults. Using hierarchical linear modeling, we analyzed data from the 2004 Health and Retirement Study, a large, nationally representative sample of US adults aged 50 years or older. We linked participant data with 2000 US Census tract data and 2004 census tract-level annual average PM2.5 concentrations. Older adults living in areas with higher PM2.5 concentrations had worse cognitive function (beta = -0.26, 95% confidence interval: -0.47, -0.05) even after adjustment for community-and individual-level social and economic characteristics. Results suggest that the association is strongest for the episodic memory component of cognitive function. This study adds to a growing body of research highlighting the importance of air pollution to cognitive function in older adults. Improving air quality in large metropolitan areas, where much of the aging US population resides, may be an important mechanism for reducing age-related cognitive decline.