Correlation Between Caregiver Reports of Physical Function and Performance-based Measures in a Cohort of Older Adults With Alzheimer Disease.
Correlation Between Caregiver Reports of Physical Function and Performance-based Measures in a Cohort of Older Adults With Alzheimer Disease.
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DOI：
10.1097/wad.0000000000000101
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发表时间：
2016-04
影响因子：
2.1
通讯作者：
Callahan CM
中科院分区：
文献类型：
--
作者：
Bernard BL;Bracey LE;Lane KA;Ferguson DY;LaMantia MA;Gao S;Miller DK;Callahan CM
本报告的目的是确定与照顾者报告的身体功能的老年人与阿尔茨海默氏病（AD）的身体功能，并检查这些协会是否不同的患者的认知功能水平之间的关联性能为基础的措施。受试者包括180名参加临床试验的患者-护理人员，该临床试验测试了职业治疗干预加上指南级护理对延迟阿尔茨海默病老年人功能衰退的影响。阿尔茨海默病合作研究组日常生活活动量表（ADCS-ADL）是阿尔茨海默病患者报告的主要指标。基于表现的测量包括短体力活动成套测验（SPPB）和短便携式肌肉减少症测量（SPSM）。协方差分析（ANCOVA）模型被用来确定每个物理性能指标与ADCS-ADL的关联，调整认知功能和其他协变量。我们发现，在所有认知功能水平上，自我报告和观察到的基于表现的测量之间存在显著相关性，认知水平最低的患者组的相关性最高。这些发现支持使用代理报告来评估老年AD患者的身体功能。
The objectives of this report are to determine the association between performance-based measures of physical function with caregiver reports of physical function in older adults with Alzheimer’s disease (AD) and to examine whether those associations vary by the level of patients’ cognitive functioning. Subjects included 180 patient-caregiver dyads who are enrolled in a clinical trial testing the impact of an occupational therapy intervention plus guideline-level care to delay functional decline among older adults with Alzheimer’s disease. The primary caregiver-reported measure is the Alzheimer’s Disease Cooperative Study Group Activities of Daily Living Inventory (ADCS-ADL). Performance-based measures include the Short Physical Performance Battery (SPPB) and the Short Portable Sarcopenia Measure (SPSM). Analysis of covariance (ANCOVA) models were used to determine the associations of each physical performance measure with ADCS-ADL, adjusting for cognition function and other covariates. We found significant correlations between caregiver-reports and observed performance-based measures across all levels of cognitive function, with patients in the lowest cognitive group showing the highest correlation. These findings support the use of proxy reports to assess physical function among older adults with AD.