DETERMINANTS OF DOPPLER INDEXES OF LEFT-VENTRICULAR DIASTOLIC FUNCTION IN NORMAL SUBJECTS (THE FRAMINGHAM HEART-STUDY)
DETERMINANTS OF DOPPLER INDEXES OF LEFT-VENTRICULAR DIASTOLIC FUNCTION IN NORMAL SUBJECTS (THE FRAMINGHAM HEART-STUDY)
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DOI：
10.1016/0002-9149(92)91199-e
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发表时间：
1992-08-15
影响因子：
2.8
通讯作者：
SUTTON, MS
中科院分区：
文献类型：
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作者：
BENJAMIN, EJ;LEVY, D;SUTTON, MS
正常多普勒值和左心室（LV）舒张功能的决定因素在健康受试者尚未完全阐明。研究对象来自心脏研究，以描述舒张功能的超声心动图多普勒指数的参考值和决定因素。127名随机选择的、严格定义的正常受试者，按性别和年龄大致均匀分布，年龄从30岁到80岁，用多普勒超声心动图进行了研究。给出了7个常用的左室舒张功能多普勒指标的正常值。左室舒张功能的多普勒指数随年龄变化显著;早期充盈峰值速度除以晚期充盈峰值速度（峰值速度E/A）的范围从30岁受试者的平均值2.08 ± 0.55到80岁受试者的平均值0.84 ± 0.29。A峰值速度E/A比值
Normative Doppler values and determinants of left ventricular (LV) diastolic function in healthy subjects have not been fully elucidated. Subjects from the Framingham Heart Study were examined to describe reference values and determinants of echocardiographic Doppler indexes of diastolic function. One hundred twenty-seven randomly selected, rigorously defined, normal subjects, approximately evenly distributed by sex and age from the third through the eighth decades were studied by Doppler echocardiography. Normative values for 7 frequently used Doppler indexes of LV diastolic function are presented. Doppler indexes of LV diastolic function change dramatically with age; the peak velocity of early filling divided by late filling (peak velocity E/A) ranges from a mean of 2.08 +/- 0.55 for subjects in their third decade to 0.84 +/- 0.29 for those in their eighth decade. A peak velocity E/A ratio