Trends in Antibiotic Use in United States Hospitals During the Coronavirus Disease 2019 Pandemic.
Trends in Antibiotic Use in United States Hospitals During the Coronavirus Disease 2019 Pandemic.
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DOI：
10.1093/ofid/ofab236
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发表时间：
2021-06
影响因子：
4.2
通讯作者：
Kabbani S
中科院分区：
文献类型：
--
作者：
Rose AN;Baggs J;Wolford H;Neuhauser MM;Srinivasan A;Gundlapalli AV;Reddy S;Kompaniyets L;Pennington AF;Grigg C;Kabbani S
我们描述了2019年冠状病毒病住院患者中抗生素的使用情况(新冠肺炎)。大多数新冠肺炎住院患者接受了抗生素治疗。我们还描述了2020年与2019年相比，医院范围内抗生素的使用情况，按医院新冠肺炎负担分层。尽管抗生素的总使用量在两年间有所下降，但随着新冠肺炎负担的增加，某些抗生素的使用量增加了。从2020年3月到10月，大多数新冠肺炎患者接受了抗生素治疗，通常是用于治疗下呼吸道感染的抗生素。随着新冠肺炎负担的增加，这些代理商的设施层面使用量增加。管理计划的弹性对于优化治疗和结果至关重要。
We described antibiotic use among inpatients with coronavirus disease 2019 (COVID-19). Most COVID-19 inpatients received antibiotic therapy. We also described hospital-wide antibiotic use during 2020 compared with 2019, stratified by hospital COVID-19 burden. Although total antibiotic use decreased between years, certain antibiotic use increased with higher COVID-19 burden. From March to October 2020, most inpatients with COVID-19 received antibiotics, frequently those used to treat lower respiratory infections. Facility-level use of these agents increased with higher COVID-19 burden. Resiliency of stewardship programs is critical to optimize treatment and outcomes.