Measurements and detection of abdominal aortic aneurysm growth: Accuracy and reproducibility of a segmentation software
Measurements and detection of abdominal aortic aneurysm growth: Accuracy and reproducibility of a segmentation software
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DOI：
10.1016/j.ejrad.2011.04.044
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发表时间：
2012-08-01
影响因子：
3.3
通讯作者：
Soulez, Gilles
中科院分区：
文献类型：
--
作者：
Kauffmann, Claude;Tang, An;Soulez, Gilles
目的：验证用于测量腹主动脉瘤(AAA)直径、体积和体积随时间增长的软件的重复性和准确性。材料和方法：测试一种可在计算机断层血管成像(CTA)上进行AAA分割、直径和体积测量的软件。对28例有连续2次CTA检查的AAA患者进行了验证。一名资深放射科医生对所有56个CTA进行了两次分割，3名医学生进行了一次分割。通过组内相关系数(ICC)计算D-max和体积值在观察者内和观察者间的重复性。系统误差采用Bland-Altman分析进行评定。结果：治疗前平均Dmax为49.6±-6.2 mm，平均Dmax为117.2±36.2ml，随访时平均Dmax为53.6±-7.9 mm，平均Dmax为139.6±56.3ml。在基线和随访检查之间，容量增长(17.3%)高于D-max进展(8.0%)(p<；.0001)。对于资深放射科医生，观察者内部的D-max和体积测量的ICC分别估计为0.997(>；=0.991)和1.000(>；=0.999)。总体观察者间D-max和体积测量的ICC估计分别为0.995(0.990-0.997)和0.999(>；0.999)。Bland-Altman分析表明，阅读器之间的一致性很好，重复性系数
Purpose: To validate the reproducibility and accuracy of a software dedicated to measure abdominal aortic aneurysm (AAA) diameter, volume and growth over time.Materials and methods: A software enabling AAA segmentation, diameter and volume measurement on computed tomography angiography (CTA) was tested. Validation was conducted in 28 patients with an AAA having 2 consecutive CTA examinations. The segmentation was performed twice by a senior radiologist and once by 3 medical students on all 56 CTAs. Intra and inter-observer reproducibility of D-max and volumes values were calculated by intraclass correlation coefficient (ICC). Systematic errors were evaluated by Bland-Altman analysis. Differences in D-max and volume growth were compared with paired Student's t-tests.Results: Mean D-max and volume were 49.6 +/- 6.2 mm and 117.2 +/- 36.2 ml for baseline and 53.6 +/- 7.9 mm and 139.6 +/- 56.3 ml for follow-up studies. Volume growth (17.3%) was higher than D-max progression (8.0%) between baseline and follow-up examinations (p < .0001). For the senior radiologist, intra-observer ICC of D-max and volume measurements were respectively estimated at 0.997 (>= 0.991) and 1.000 (>= 0.999). Overall inter-observer ICC of D-max and volume measurements were respectively estimated at 0.995 (0.990-0.997) and 0.999 (>0.999). Bland-Altman analysis showed excellent inter-reader agreement with a repeatability coefficient