Subacute sensory neuronopathy associated with small cell lung carcinoma: diagnosis aided by autoimmune serology.
Subacute sensory neuronopathy associated with small cell lung carcinoma: diagnosis aided by autoimmune serology.
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DOI：
10.1016/s0025-6196(12)62661-5
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发表时间：
1988
影响因子：
8.9
通讯作者：
David W. Kimmel;Brian P. O'Neill;V. A. Lennon
中科院分区：
文献类型：
--
作者：
David W. Kimmel;Brian P. O'Neill;V. A. Lennon
在两例亚急性感觉神经病变伴肺小细胞癌的患者中，在高度稀释的血清（分别为1/500和1/ 2000）中发现异常和独特的抗核抗体，其反应性仅限于神经元核，这有助于诊断副肿瘤综合征。胸部磁共振成像在检测两种肺癌方面都很有用。
In two patients with subacute sensory neuronopathy associated with small cell carcinoma of the lung, the diagnosis of the paraneoplastic syndrome was aided by the finding, in highly diluted serum (1/500 and 1/2,000, respectively), of unusual and distinctive antinuclear antibodies with reactivity restricted to neuronal nuclei. Magnetic resonance imaging of the chest was instrumental in detecting both lung cancers.