Molecular interactions in collagen and chitosan blends
Molecular interactions in collagen and chitosan blends
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DOI：
10.1016/s0142-9612(03)00595-7
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发表时间：
2004-02-01
期刊：
影响因子：
14
通讯作者：
Wess, TJ
中科院分区：
文献类型：
--
作者：
Sionkowska, A;Wisniewski, M;Wess, TJ
胶原蛋白和壳聚糖 (CC) 之间的分子相互作用有可能生产具有新颖特性的生物复合材料。我们通过粘度测定、广角 X 射线散射和傅里叶变换红外光谱表征了 CC 配合物中的分子相互作用。研究发现，CC 在分子水平上是可混溶的，并且各组分之间表现出相互作用；CC 共混物的 X 射线衍射表明，随着壳聚糖含量的增加，CC 膜中的胶原螺旋结构消失。随着壳聚糖含量的降低，非线性粘性行为被解释为作为 CC 复合物形成的第三结构相的证据。胶原蛋白与壳聚糖的混合使得生产用于潜在生物医学应用的新型定制材料成为可能。 (C) 2003 Elsevier Ltd. 保留所有权利。
Molecular interactions between collagen and chitosan (CC) have the potential to produce biocomposites with novel properties. We have characterised the molecular interactions in CC complexes by viscometry, wide angle X-ray scattering and Fourier transform infrared spectroscopy. It was found that CC are miscible at the molecular level and exhibit interactions between the components;, X-ray diffraction of CC blends indicate that the collagen helix structure is lost in CC films with increasing chitosan content. Non-linear viscometic behaviour with decreasing chitosan content is interpreted as evidence of a third structural phase formed as a complex of CC. The blending of collagen with chitosan gives the possibility of producing new bespoke materials for potential biomedical applications. (C) 2003 Elsevier Ltd. All rights reserved.