Mild cognitive impairment -: beyond controversies, towards a consensus:: report of the International Working Group on Mild Cognitive Impairment
Mild cognitive impairment -: beyond controversies, towards a consensus:: report of the International Working Group on Mild Cognitive Impairment
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DOI：
10.1111/j.1365-2796.2004.01380.x
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发表时间：
2004-09-01
影响因子：
11.1
通讯作者：
Petersen, RC
中科院分区：
文献类型：
--
作者：
Winblad, B;Palmer, K;Petersen, RC
第一届重要研讨会于 2003 年 9 月 2-5 日在瑞典斯德哥尔摩举行。研讨会的目的是整合关于轻度认知障碍 (MCI) 主题的临床和流行病学观点。多学科的国际专家组讨论了 MCI 的现状和未来方向，包括临床表现、认知和功能评估以及神经影像、生物标志物和遗传学的作用。国际工作组讨论了新观点的一致意见以及对管理和未来研究的建议。一般 MCI 标准的具体建议包括以下内容： (i) 该人既不正常也不痴呆； (ii) 有证据表明，随着时间的推移，客观测量的下降和/或自我和/或知情者主观报告的下降与客观认知缺陷相结合，表明认知能力下降； (iii) 日常生活活动得以保留，复杂的工具功能完好无损或受损程度最低。
The First Key Symposium was held in Stockholm, Sweden, 2-5 September 2003. The aim of the symposium was to integrate clinical and epidemiological perspectives on the topic of Mild Cognitive Impairment (MCI). A multidisciplinary, international group of experts discussed the current status and future directions of MCI, with regard to clinical presentation, cognitive and functional assessment, and the role of neuroimaging, biomarkers and genetics. Agreement on new perspectives, as well as recommendations for management and future research were discussed by the international working group. The specific recommendations for the general MCI criteria include the following: (i) the person is neither normal nor demented; (ii) there is evidence of cognitive deterioration shown by either objectively measured decline over time and/or subjective report of decline by self and/or informant in conjunction with objective cognitive deficits; and (iii) activities of daily living are preserved and complex instrumental functions are either intact or minimally impaired.