In Turn or in Reverse Palladium-Catalyzed Carbonyl Allylation and Diels-Alder Reaction by 2-Methylene-3-buten-1-ol
In Turn or in Reverse Palladium-Catalyzed Carbonyl Allylation and Diels-Alder Reaction by 2-Methylene-3-buten-1-ol
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DOI：
10.1246/cl.1993.1199
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发表时间：
1993-07
影响因子：
1.6
通讯作者：
Y. Masuyama;M. Fuse;Y. Kurusu
中科院分区：
文献类型：
--
作者：
Y. Masuyama;M. Fuse;Y. Kurusu
使用PdCl 2（PhCN）2-SnCl 2，2-亚甲基-3-丁烯-2-醇引起各种醛的羰基烯丙基化，得到1-取代-3-亚甲基-4-戊烯-1-醇;这些与亲二烯体的Diels-Alder反应产生1-（2-羟乙基）环己烯。2-亚甲基-3-丁烯-1-醇与亲二烯体发生Diels-Alder反应，然后进行羰基烯丙基化，生成结构异构的1-亚甲基-2-（羟甲基）环己烷。
Using PdCl2(PhCN)2-SnCl2, 2-methylene-3-buten-2-ol causes carbonyl allylation of various aldehydes to afford 1-substituted-3-methylene-4-penten-1-ols; the Diels-Alder reaction of those with dienophiles produces 1-(2-hydroxyethyl)cyclohexenes. Diels-Alder reaction of 2-methylene-3-buten-1-ol with dienophiles followed by carbonyl allylation produces structurally isomeric 1-methylene-2-(hydroxymethyl)cyclohexanes.