A Wireless Implantable Opto-Electro Neural Interface ASIC for Simultaneous Neural Recording and Stimulation

A Wireless Implantable Opto-Electro Neural Interface ASIC for Simultaneous Neural Recording and Stimulation
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DOI:
10.1109/cicc57935.2023.10121181
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发表时间:
2023-04
期刊:
2023 IEEE Custom Integrated Circuits Conference (CICC)
影响因子:
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通讯作者:
Linran Zhao;Yan Gong;Wei Shi;R. Stephany;Wen Li;Y. Jia
Linran Zhao;Yan Gong;Wei Shi;R. Stephany;Wen Li;Y. Jia
中科院分区:
其他
文献类型:
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作者:
Linran Zhao;Yan Gong;Wei Shi;R. Stephany;Wen Li;Y. Jia

文献摘要

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光遗传学的最新进展使光刺激能够可逆地控制遗传靶向的特定神经元的活性。挑战无线功率在动力传递方面,可以消除tethers,电池和局限性,因此,能量效率的光刺激电路还需要刺激诱导的神经记录和敏感性的刺激性。 SFE可以忍受大型伪像,因此我们提出了一种新型的无线植入光电(WIOE)神经界面,具有耐受的SFE的特征,能源有效的光刺激以及无线和无线操作。
Recent advances in optogenetics enable optical stimulation that uses light to reversibly control the activity of the genetically targeted specific neurons. Optical stimulation has distinct advantages of cell specificity, high temporal precision, and rapid reversibility, compared to electrical stimulation [1] –[4]. LEDs typically require high instantaneous current in the order of mA level to emit sufficient light for effective optical stimulation. Such a power-consuming function will challenge wireless power transmission. Wireless operation in terms of power delivery and data transmission is highly desired for eliminating tethers, batteries, and limitations during in vivo studies. Thus, energy-efficiency optical stimulation circuits are required. In addition, the stimulation-induced artifacts can corrupt neural recording and lead to saturation of sensing frontend (SFE) circuits. Neural interface ASIC for simultaneous neural recording and stimulation requires an SFE that can tolerate large artifacts. Hence, we present a novel wireless implantable opto-electro (WIOE) neural interface ASIC with features of artifact-tolerant SFE, energy-efficient optical stimulation, and wireless and battery-free operation.