ASSOCIATION OF EARLY-ONSET CORONARY HEART-DISEASE IN SOUTH ASIAN MEN WITH GLUCOSE-INTOLERANCE AND HYPERINSULINEMIA
ASSOCIATION OF EARLY-ONSET CORONARY HEART-DISEASE IN SOUTH ASIAN MEN WITH GLUCOSE-INTOLERANCE AND HYPERINSULINEMIA
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DOI：
10.1161/01.cir.87.1.152
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发表时间：
1993-01-01
期刊：
影响因子：
37.8
通讯作者：
MCKEIGUE, PM
中科院分区：
文献类型：
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作者：
MCKEIGUE, PM
背景资料。在海外定居的南亚人(印度人、巴基斯坦人、孟加拉人)的冠心病发病率高于其他民族。我们测试了这样一种假设，即这种额外风险是由与胰岛素抵抗相关的代谢紊乱引起的。方法和结果。在伦敦，1,421名南亚男性和1,515名欧洲男性接受了索索尔研究，年龄在40岁到69岁之间。南亚人缺血性心电异常的发生率高于欧洲人(17%比12%，P
Background. Rates of coronary heart disease are higher in South Asians (Indians, Pakistanis, an Bangladeshis) settled overseas than in other ethnic groups. We tested the hypothesis that this excess risk results from metabolic disturbances associated with insulin resistance.Methods and Results. There were 1,421 South Asian men and 1,515 European men aged 40-69 years in London examined in the Southall Study. Prevalence of ischemic ECG abnormalities was higher in South Asians than in Europeans (17% versus 12%, p