Alterations in semen parameters of toll collectors working at motorways: does diesel exposure induce detrimental effects on semen?
Alterations in semen parameters of toll collectors working at motorways: does diesel exposure induce detrimental effects on semen?
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DOI：
10.1111/j.1439-0272.2008.00867.x
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发表时间：
2008-12-01
期刊：
影响因子：
2.4
通讯作者：
Cam, M.
中科院分区：
文献类型：
--
作者：
Guven, A.;Kayikci, A.;Cam, M.
空气污染目前被认为是精液参数受损的一个重要原因。本研究的目的是调查交通污染物，主要是柴油暴露，对精液分析的可能影响。共有38名在高速公路上工作的收费员组成了研究小组。同时，35名办公室工作人员组成对照组。排除标准包括精索静脉曲张、慢性疾病等可能影响精子产生的因素。两组之间在吸烟方面没有差异。按照世卫组织指南进行常规精液分析。精液分析结果显示，研究组中分别有8名和7名男性活力下降和精子数量减少。此外，同一组的一名男性同时出现了运动能力下降和精子数量低的异常。然而，对照组的两名男性有轻微的运动能力缺陷，一名男性精子数量低。两组间异常精子数和活力差异有统计学意义（P = 0.002和P = 0.003）。同样，研究组正常形态的精子细胞比例明显低于对照组（P = 0.001）。这一观察结果表明，空气污染，特别是柴油暴露可能对精子参数产生有害影响。
Air pollution is contemporarily considered to be a significant cause in impairing semen parameters. The aim of this study was to investigate possible effects of traffic pollutants, mainly the diesel exposure, on semen analysis. A total of 38 men working as toll collectors at motorways formed the study group. Simultaneously, 35 men working as office personnel constituted the control group. Factors including varicocele, chronic diseases that can affect sperm production were the exclusion criteria. No difference regarding smoking was present between the groups. Usual semen analysis according to WHO guidelines was performed. The results of semen analysis revealed decreased motility and low sperm counts in eight and seven men from the study group respectively. Besides, a man from the same group had combined abnormality of decreased motility and low sperm count. However, two men from the control group had slight motility defect and one had low sperm count. The differences regarding the abnormal sperm count and motility were significant between the groups (P = 0.002 and P = 0.003, respectively). Similarly, the ratio of sperm cells with normal morphology was significantly lower in the study group than that in the control group (P = 0.001). This observation proposes that air pollution particularly diesel exposure may have detrimental effects on sperm parameters.