Low episodic memory performance as a premorbid marker of depression:: evidence from a 3-year follow-up
Low episodic memory performance as a premorbid marker of depression:: evidence from a 3-year follow-up
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DOI：
10.1111/j.1600-0447.2006.00932.x
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发表时间：
2007-06-01
影响因子：
6.7
通讯作者：
Larsson, M.
中科院分区：
文献类型：
--
作者：
Airaksinen, E.;Wahlin, A.;Larsson, M.
目的：为了研究低情节记忆分数作为一个潜在的危险因素depress.Method：一个基于人口的样本的非抑郁症的个人（20-64岁）进行了重新检查3年后，初步筛选（n = 708）。在基线时，收集有关情景记忆评分、人口统计学和社会经济因素、酒精使用和焦虑诊断的信息。在基线和随访时收集抑郁症诊断的数据。Logistic回归，在三个独立的研究组中进行，这些研究组根据三项情景记忆评估进行定义（即自由回忆+线索回忆，自由回忆，线索回忆）在记忆测试中得分最低或最高的25名个体中，结论：情节记忆成绩的降低早于抑郁症的诊断，可作为抑郁症的一个病前标志。
Objective: To examine low episodic memory scores as a potential risk factor for depression.Method: A population-based sample of non-depressed individuals (20-64 years) were re-examined 3 years after an initial screening (n = 708). At baseline, information on episodic memory scores, demographic and socioeconomic factors, alcohol use and anxiety diagnoses was collected. The data for depression diagnoses were collected at both baseline and follow-up.Results: Logistic regressions, conducted on three separate study groups that were defined according to three assessments of episodic memory (i.e. free + cued recall, free recall, cued recall) among individuals who scored in the 25 lowest or highest percentiles in the memory tests, revealed that low episodic memory performance defined as the sum of free and cued recalls of organizable words constitutes a risk of depression diagnosis 3 years later.Conclusion: Low episodic memory performance predated depressive diagnosis and might be considered as a premorbid marker of depression.