Biomineralization of uniform gallium oxide rods with cellular compatibility.
Biomineralization of uniform gallium oxide rods with cellular compatibility.
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DOI：
10.1021/ic900420m
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发表时间：
2009-06
影响因子：
4.6
通讯作者：
Danhong Yan;G. Yin;Zhongbing Huang;Xiaoming Liao;Yunqing Kang;Yadong Yao;B. Hao;Jianwen Gu;
中科院分区：
文献类型：
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作者：
Danhong Yan;G. Yin;Zhongbing Huang;Xiaoming Liao;Yunqing Kang;Yadong Yao;B. Hao;Jianwen Gu;
以丝素蛋白(SF)为模板，通过简单的生物矿化方法制备了包覆有丝素蛋白(SF)的单分散单晶α-GaOOH棒材。分别在600℃和800℃下对α-GaOOH棒进行热处理，得到了碳包覆的α-Ga(2)O(3)和β-Ga(2)O(3)棒。体外细胞毒性研究表明，在0.1 mg/mL以下制备的氧化镓棒对L929、Hela和HaCat细胞的增殖没有明显的抑制作用。基于它们优异的发光性能和细胞兼容性，生物光电子器件的应用前景是可以预见的。
Monodispersed single crystalline alpha-GaOOH rods coated by silk fibroin (SF) have been prepared via a facile biomineralization process in the template of SF peptide. The carbon-coated alpha-Ga(2)O(3) and beta-Ga(2)O(3) rods are obtained by thermal treatment of the alpha-GaOOH rods at 600 and 800 degrees C, respectively. In vitro cytotoxicity studies of these gallium oxide rods showed no significant effect leading to restraint of cell proliferation of L929, Hela, and HaCat cells in less than 0.1 mg/mL prepared rods. On the basis of their excellent luminescence emission properties and cellular compatibilities, possible applications for bio-optoelectronic devices can be envisioned.