Defining the metabolic syndrome in children and adolescents: Will the real definition please stand up?

Defining the metabolic syndrome in children and adolescents: Will the real definition please stand up?
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DOI:
10.1016/j.jpeds.2007.07.056
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发表时间:
2008-02-01
影响因子:
5.1
通讯作者:
Li, Chaoyang
Li, Chaoyang
中科院分区:
医学2区
文献类型:
--
作者:
Ford, Earl S.;Li, Chaoyang

文献摘要

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目的 回顾代谢综合征定义在儿童和青少年研究中的使用,并回顾使用因子分析检查心脏代谢变量结构的前沿研究结果。研究设计文献综述。结果见于 27 篇出版物。作者使用了 40 种代谢综合征的独特定义。这些定义大部分是根据国家胆固醇教育计划制定的成人定义改编的。在使用探索性因素分析的 11 项研究中,成分数量从 5 到 19 个不等,确定的因素数量从 1 到 5 个不等。 结论 代谢综合征的多种定义的使用有力地支持了标准儿科定义的制定。
Objectives To review the use of definitions of the metabolic syndrome in studies of children and adolescents and to review results front studies that used factor analysis to examine structure among cardiometabolic variables.Study design Literature review.Results In 27 publications. authors used 40 unique definitions of the metabolic syndrome. Most of these definitions were adaptations of the adult definition developed by the National Cholesterol Education Program. In 11 studies that used exploratory factor analysis, the number of components ranged from 5 to 19, and the number of factors identified ranged from 1 to 5.Conclusions The use of multiple definitions of the metabolic syndrome argues strongly for the development of a standard pediatric definition.