Oral symptoms including dental erosion in gastroesophageal reflux disease are associated with decreased salivary flow volume and swallowing function
Oral symptoms including dental erosion in gastroesophageal reflux disease are associated with decreased salivary flow volume and swallowing function
复制标题
DOI：
10.1007/s00535-011-0515-6
复制
发表时间：
2012-04-01
影响因子：
6.3
通讯作者：
Sekine, Joji
中科院分区：
文献类型：
--
作者：
Yoshikawa, Hiroo;Furuta, Kenji;Sekine, Joji
本研究旨在探讨唾液流量和吞咽功能对胃食管反流病（GERD）患者口腔症状（包括牙侵蚀）的影响，研究对象为40例GERD患者和30例健康对照者（年轻组15例，老年组15例）。详细的医疗，饮食和牙科历史，以确定个人的行为习惯可能与牙齿侵蚀。口腔检查评估牙齿侵蚀，并确定腐烂，缺失，填充（DMF）指数，牙龈炎的乳头，边缘，附着（PMA）指数和简化口腔卫生指数（OHI-S）的分数。唾液流量和吞咽功能分别采用Saxon试验和重复唾液吞咽试验进行评价，3组间DMF指数和OHI-S评分差异有统计学意义。胃食管反流病组与两个对照组之间的PMA指数有显著性差异。GERD组的牙侵蚀患病率为24.3%（对照组为0%）。未发现牙齿侵蚀的发生率与饮食史或行为习惯之间存在特定关系。胃食管反流病组的Saxon试验结果显著低于两个对照组。与两个对照组相比，GERD组的吞咽频率显著降低，首次吞咽时间显著延长。GERD的口腔症状可能与唾液流量或吞咽功能受损有关。治疗由唾液流量减少引起的口腔干燥和吞咽功能的康复可能适用于GERD患者。
This preliminary clinical study aimed to evaluate the effects of salivary flow volume and swallowing function on oral symptoms including dental erosion in gastroesophageal reflux disease (GERD).The subjects were 40 GERD patients and 30 (15 younger, 15 older) healthy controls. Detailed medical, dietary, and dental histories were obtained to identify individual behavioral habits potentially associated with dental erosion. Oral examination evaluated dental erosion and determined scores for the decayed, missing, filled (DMF) index, the papillary, marginal, attached (PMA) index for gingivitis, and the Simplified Oral Hygiene Index (OHI-S). Salivary flow volume and swallowing function were evaluated by the Saxon test and repetitive saliva swallowing test, respectively.The DMF index and OHI-S scores differed significantly between all 3 groups. The PMA index was significantly different between the GERD group and the two control groups. The prevalence of dental erosion was 24.3% in the GERD group (0% in the control groups). No specific relationship was found between the incidence of dental erosion and dietary history or behavioral habits. The Saxon test results were significantly lower in the GERD group than in both the control groups. Frequency of swallowing was significantly lower and time to first swallow was significantly longer in the GERD group than in the two control groups.Oral symptoms in GERD are likely to be associated with impaired salivary flow volume or swallowing function. Treatment for the oral dryness induced by reduced salivary flow volume and rehabilitation for swallowing function could be indicated in patients with GERD.