Direct liquid-phase phenol-to-aniline amination using Pd/C
Direct liquid-phase phenol-to-aniline amination using Pd/C
复制标题
DOI：
10.1039/c8cy00193f
复制
发表时间：
2018-05-21
影响因子：
5
通讯作者：
De Vos, Dirk E.
中科院分区：
文献类型：
--
作者：
Cuypers, Thomas;Tomkins, Patrick;De Vos, Dirk E.
在这里，我们报告的第一个直接胺化苯酚与氨成伯苯胺在液相中。为此，Pd/C被证明是最合适的催化剂。优化的反应参数导致非常有选择性和可持续的生产伯苯胺的产率高达95%。
Here, we report the first direct amination of phenol with ammonia into primary anilines in the liquid phase. For this, Pd/C was demonstrated to be the most suitable catalyst. Optimization of the reaction parameters resulted in very selective and sustainable production of primary anilines with yields of up to 95%.