NO DIFFERENCE IN COGNITIVE PERFORMANCE BETWEEN PHASES OF THE MENSTRUAL-CYCLE

NO DIFFERENCE IN COGNITIVE PERFORMANCE BETWEEN PHASES OF THE MENSTRUAL-CYCLE
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DOI:
10.1016/0306-4530(93)90045-m
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发表时间:
1993-01-01
影响因子:
3.7
通讯作者:
LEE, PA
LEE, PA
中科院分区:
医学2区
文献类型:
--
作者:
GORDON, HW;LEE, PA

文献摘要

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三组女性在文字序列或视觉空间神经心理测试中的表现没有差异。在任何测试中,月经周期的各个阶段也没有差异。本研究的设计是在正常月经周期的定期月经妇女,并在可比的时间点口服避孕药的妇女和闭经的妇女之间的verbosequential和视觉空间神经心理学测试的妇女的样本性能。测定各组在每个时间点的血清促黄体生成素(LH)、促卵泡激素(FSH)、雌二醇和孕酮,以记录这些激素水平。这些数据与我们实验室以前的结果一致,但与其他报告相冲突,其中认知功能的变化与雌激素的波动有关。阳性结果的唯一迹象是受试者之间促性腺激素和认知功能的弱相关性。虽然其中一些相关性重复了以前的结果,但它们很弱,应该谨慎考虑。
No differences were seen in performance on either verbosequential or visuospatial neuropsychological tests among three groups of women. There were also no differences among the phases of the menstrual cycle on any of the tests. The design of this study was to sample performance of women on verbosequential and visuospatial neuropsychological tests during phases of the normal menstrual cycle in regularly menstruating women, and at comparable time points among women taking oral contraceptives and among those who had amenorrhea. Serum leutinizing hormone (LH), follicle-stimulating hormone (FSH), estradiol, and progesterone were assayed to document these hormone levels at each time point for each group. These data are consistent with previous results in our laboratory but conflict with other reports in which shifts in cognitive function were related to fluctuations in estrogen. The only indications of positive results were weak correlations with gonadotropins and cognitive function across subjects. While some of these correlations replicated previous results, they were weak and should be considered with caution.