Acute, Severe Hepatitis Caused by Coronavirus Disease 2019: A Case Report
Acute, Severe Hepatitis Caused by Coronavirus Disease 2019: A Case Report
复制标题
DOI：
10.11150/kansenshogakuzasshi.e22026
复制
发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Naonori Maeda;N. Mori;K. Yamazawa;Natsuno Abe;Toshihide Kijima;Sanae Kishida;Rieko Sato;Eri Suzuki;Hisayo Fujita;Masashi Miharu
中科院分区：
文献类型：
--
作者：
Naonori Maeda;N. Mori;K. Yamazawa;Natsuno Abe;Toshihide Kijima;Sanae Kishida;Rieko Sato;Eri Suzuki;Hisayo Fujita;Masashi Miharu
严重肝炎在患有2019冠状病毒病（COVID-19）的儿科患者中很少见到，除非与儿童多系统炎症综合征/儿童炎症多系统综合征（MIS-C/PIMS）或严重疾病相关。在这里，我们报告了一名患有轻度COVID-19的8岁日本男孩发展为肝炎的病例。患者一般情况良好，无发热或呼吸道症状，但患有严重急性肝炎，自行消退。最近在世界范围内报告了病因不明的儿童严重急性肝炎，并在一些患者中发现了严重急性呼吸综合征冠状病毒2 （SARS-CoV-2）。然而，这是日本首次报告儿童出现与轻度COVID-19相关的严重急性肝炎病例。
Severe hepatitis is rarely seen in pediatric patients with coronavirus disease 2019 (COVID-19), except in association with multisystem inflammatory syndrome in children/pediatric inflammatory multisystem syndrome (MIS-C/PIMS) or with severe disease. Here, we present the case of an 8-year-old Japanese boy with mild COVID-19 who developed hepatitis. The patient was in good general condition without fever or respiratory symptoms, but had severe acute hepatitis that resolved spontaneously. Severe acute hepatitis of unknown etiology in children has been recently reported worldwide, and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been identified in some patients. However, this is the first case report from Japan of severe acute hepatitis associated mild COVID-19 in a child.