Electrolyte Intake and nonpharmacologic blood pressure control
Electrolyte Intake and nonpharmacologic blood pressure control
复制标题
DOI：
10.1016/s1047-2797(01)00318-0
复制
发表时间：
2002-11-01
影响因子：
5.6
通讯作者：
Bahnson, J
中科院分区：
文献类型：
--
作者：
Espeland, MA;Kumanyika, S;Bahnson, J
目得：为了表征钠和钾的摄入量和血压control.METHODS之间的关系：我们分析了重复的24小时饮食回忆和24小时尿液检测从873名老年参与者建立高血压在3年的临床试验的生活方式干预。电解质摄入量的合并估计开发使用分层测量误差模型和相关的非药物血压control.RESULTS：相对减少钠和钾的摄入量增加每个有等级关系，船舶与更好的血压控制。校正测量误差后，钠摄入量每24小时减少100 mmol与整个随访期间维持非药物血压控制的比值比为2.93 [95%置信区间：1.83，4.64]相关。钾摄入量每24小时增加50 mmol与比值比2.00相关[1.12，3.55]。这些关系是相互独立的和基线水平的摄入量。血压控制与钠摄入量最密切相关的参与者较低的收缩压和高血压的持续时间较长，与钾的舒张压升高的bypassy.Conclusions：钠和钾的摄入量发挥独立的分级影响非药物血压控制。相关的测量误差可能虚假地在这些关系之间引入依赖性。(C)2002年爱思唯尔科技有限公司
PURPOSE: To characterize relationships between sodium and potassium intakes and blood pressure control.METHODS: We analyzed repeated 24-hour diet recalls and 24-hour urine assays from 873 elderly participants with established hypertension in a 3-year clinical trial of lifestyle interventions. Pooled estimates of electrolyte intakes were developed using hierarchical measurement error models and related to nonpharmacologic blood pressure control.RESULTS: Relative decreases in sodium and increases in potassium intakes each had graded relation, ships with better blood-pressure control. After adjustment for measurement error, a 100 mmol/24-hour decrease in sodium intake was associated with an odds ratio of 2.93 [95% confidence interval: 1.83, 4.64] for maintaining nonpharmacologic blood pressure control throughout follow-up. A 50 mmol/24-hour increase in potassium intake was associated with an odds ratio of 2.00 [1.12, 3.55]. These relationships were independent of each other and of baseline levels of intakes. Blood pressure control was most strongly associated with sodium intake for participants with lower systolic blood pressures and longer duration of hypertension, and with potassium for those with elevated diastolic blood pressures.CONCLUSIONS: Sodium and potassium intakes exert independent graded influences on nonpharmacologic blood pressure control. Correlated measurement error may spuriously introduce a dependency among these relationships. (C) 2002 Elsevier Science Inc.