Facet orientation and tropism: associations with facet joint osteoarthritis and degeneratives.
Facet orientation and tropism: associations with facet joint osteoarthritis and degeneratives.
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DOI：
10.1097/brs.0b013e3181aa2acb
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发表时间：
2009-07-15
期刊：
影响因子：
3
通讯作者：
Hunter DJ
中科院分区：
文献类型：
--
作者：
Kalichman L;Suri P;Guermazi A;Li L;Hunter DJ
研究设计。横断面研究。目的。评价在社区骨折心脏研究中通过多探测器计算机断层扫描确定的腰椎小关节方向、小关节取向、小关节骨关节炎（OA）和退行性脊椎滑脱（DS）之间的关系。背景资料总结。腰椎小关节OA、DS、方法：本研究是Frachial Heart研究的一个辅助项目。3529例年龄在40 - 80岁的心脏病研究参与者接受了多探测器计算机断层扫描成像，以评估主动脉钙化。188例患者连续入组本辅助研究，以评估与腰痛相关的影像学特征。使用4级量表在L3-L4、L4-L5和L5-S1脊柱节段评价小关节OA。之间的关联小关节OA，DS，和小关节的方向，和取向进行了检查，使用多元逻辑回归模型调整年龄，性别，和身体质量index.Results.At每个脊柱水平的小关节与OA更矢状位比那些没有OA，但差异有统计学意义，只有在L4-L5脊柱水平（P= 0.0007）。在任何脊柱节段，小关节向性与小关节OA均无相关性。小关节方向与DS显著相关（0.89 [0.84-0.94]），然而，小关节取向与DS无相关性。结论：目前的研究证实了矢状方向与L4-L5和DS的腰椎小关节OA之间的显著相关性。小关节向性与小关节OA或DS的发生无关。此外，纵向研究需要了解关节突关节形态和OA之间的因果关系。
Study Design.Cross-sectional study.Objective.To evaluate the association between lumbar spine facet joint orientation, facet joint tropism, and facet joint osteoarthritis (OA) and degenerative spondylolisthesis (DS) identified by multidetector computed tomography in the community-based Framingham Heart Study.Summary of Background Data.The association between lumbar facet joint OA, DS, and facet orientation and tropism remains unclear.Methods.This study was an ancillary project to the Framingham Heart Study. A sample of 3529 participants of the Framingham Heart Study aged 40 to 80 underwent multidetector computed tomography imaging to assess aortic calcification. One hundred eighty-eight individuals were consecutively enrolled in this ancillary study to assess radiographic features associated with low back pain. Facet joint OA was evaluated at the L3–L4, L4–L5, and L5–S1 spinal levels, using a 4-grade scale. The association between facet joint OA, DS, and facet orientation, and tropism was examined using multiple logistic regression models adjusting for age, sex, and body mass index.Results.At each spinal level the facet joints with OA were more sagittally oriented than those without OA, but the difference was statistically significant only at L4–L5 spinal level (P= 0.0007). Facet tropism did not show an association with facet joint OA at any spinal level. Facet orientation was significantly associated with DS (0.89 [0.84–0.94]), however, facet tropism showed no association with DS.Conclusions.The current study confirms a significant association between sagittal orientation and OA of the lumbar facet joints at L4–L5 and DS. Facet tropism was not associated with occurrence of facet joint OA or DS. Additional, longitudinal studies are needed to understand the causal relationship between facet joint morphology and OA.