Habitual physical activity in Dutch children and adolescents with haemophilia
Habitual physical activity in Dutch children and adolescents with haemophilia
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DOI：
10.1111/j.1365-2516.2011.02555.x
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发表时间：
2011-09-01
期刊：
影响因子：
3.9
通讯作者：
Fischer, K.
中科院分区：
文献类型：
--
作者：
Groen, W. G.;Takken, T.;Fischer, K.
对于血友病患者来说，积极的生活方式对于保持肌肉骨骼健康和预防慢性疾病（如心血管疾病）非常重要。因此，我们研究了患有血友病的荷兰儿童和青少年的身体活动水平及其与有氧健身和关节健康的关系。47名血友病男孩（818岁）参加了研究。身体活动使用可调整活动问卷（MAQ）进行测量，并与一般人群进行比较。有氧健身是用峰值摄氧量（VO 2 peak）来确定的。使用血友病关节健康评分（HJHS）测量关节健康。通过相关分析评估了身体活动、关节健康和有氧健身之间的关系。受试者年龄为12.5岁（SD 2.9），体重指数（BMI）为19.5（SD 3.1; z评分0.5），中位HJHS评分为0（范围0-6）。骑自行车、体育课和游泳是最常报告的活动（分别为86%、69%和50%）。与非严重血友病儿童相比，严重血友病儿童参加足球比赛明显较少，参加游泳比赛较多。血友病严重程度之间的体力活动水平相似，与一般人群相当。VO 2峰值kg（-1）略低于健康男孩（42.9 +/- 8.6 vs. 46.9 +/- 1.9 mL kg（-1）min（-1）; P = 0.03）。关节健康、有氧健身和身体活动没有相关性。患有血友病的荷兰儿童从事各种不同强度的活动，并表现出与普通人群相当的体力活动水平。有氧健身得到了很好的保持，并没有显示出与身体活动水平或关节健康的关联。
For patients with haemophilia, a physically active lifestyle is important to maintain musculoskeletal health and to prevent chronic diseases, such as cardiovascular disease. Therefore, we studied physical activity levels, in Dutch children and adolescents with haemophilia as well as its association with aerobic fitness and joint health. Forty-seven boys with haemophilia (aged 818) participated. Physical activity was measured using the Modifiable Activity Questionnaire (MAQ) and was compared with the general population. Aerobic fitness was determined using peak oxygen uptake (VO2peak). Joint health was measured using the Haemophilia Joint Health Score (HJHS). Associations between physical activity, joint health and aerobic fitness were evaluated by correlation analysis. Subjects were 12.5 (SD 2.9) years old, had a Body Mass Index (BMI) of 19.5 (SD 3.1; z-score 0.5) and a median HJHS score of 0 (range 0-6). Cycling, physical education and swimming were most frequently reported (86%, 69% and 50% respectively). Children with severe haemophilia participated significantly less in competitive soccer and more in swimming than children with non-severe haemophilia. Physical activity levels were similar across haemophilia severities and comparable to the general population. VO2peak kg(-1) was slightly lower than healthy boys (42.9 +/- 8.6 vs. 46.9 +/- 1.9 mL kg(-1) min(-1); P = 0.03). Joint health, aerobic fitness and physical activity showed no correlation. Dutch children with haemophilia engaged in a wide range of activities of different intensities and showed comparable levels of physical activity to the general population. Aerobic fitness was well preserved and showed no associations with physical activity levels or joint health.