Supracricoid partial laryngectomy after failed laryngeal radiation therapy
Supracricoid partial laryngectomy after failed laryngeal radiation therapy
复制标题
DOI：
10.1097/00005537-199604000-00019
复制
发表时间：
1996-04-01
期刊：
影响因子：
2.6
通讯作者：
Brasnu, D
中科院分区：
文献类型：
--
作者：
Laccourreye, O;Weinstein, G;Brasnu, D
对 12 名在喉放射治疗 (RT) 失败后接受环上部分喉切除术 (SCPL) 的患者进行了评估。没有一个复发肿瘤适合垂直或水平部分喉切除术。分析气管切开插管、口服营养、发病率、局部控制和生存情况，主要并发症包括软骨膜炎（2例）、喉狭窄（2例）和吸入性肺炎（1例），皮肤粘膜瘘和环杓关节强直均未发生。所有病例均未涉及切除边缘。 Kaplan-Meier 的 3 年精算生存率和当地控制估计值为 83.3%。挽救性全喉切除术可实现总体 100% 的局部控制率和 75% 的喉保留率。这份初步报告表明，对于不适合垂直或水平部分喉切除术的喉部 RT 失败患者，在提倡挽救性全喉切除术之前应讨论 SCPL 手术，有必要进一步系列分析喉 RT 失败后各种 SCPL 手术的作用和局限性。
Twelve patients managed with supracricoid partial laryngectomies (SCPLs) after failed laryngeal radiation therapy (RT) were evaluated. None of the recurrent tumors were amenable to vertical or horizontal partial laryngectomy. Results were analyzed for tracheostomy decannulation, oral alimentation, morbidity, local control, and survival, Major complications included perichondritis (2 patients), laryngeal stenosis (2 patients), and pneumonia from aspiration (1 patient), Mucocutaneous fistula and cricoarytenoid joint ankylosis were riot encountered. Margins of resection were uninvolved in all cases. The Kaplan-Meier 3-year actuarial survival and local control estimate was 83.3%. Salvage total laryngectomy allowed for an overall 100% local control rate and a 75% laryngeal preservation rate.This preliminary report suggests that, in patients with failed laryngeal RT not amenable to vertical or horizontal partial laryngectomy, the SCPL procedures should be discussed before advocating salvage total laryngectomy, Further series analyzing the role and limitations of the various SCPL procedures after failed laryngeal RT are warranted.