GENETIC-VARIATION IN RECOMBINATION IN DROSOPHILA .1. RESPONSES TO SELECTION AND PRELIMINARY GENETIC-ANALYSIS
GENETIC-VARIATION IN RECOMBINATION IN DROSOPHILA .1. RESPONSES TO SELECTION AND PRELIMINARY GENETIC-ANALYSIS
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DOI：
10.1038/hdy.1985.10
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发表时间：
1985-01-01
期刊：
影响因子：
3.8
通讯作者：
CHARLESWORTH, D
中科院分区：
文献类型：
--
作者：
CHARLESWORTH, B;CHARLESWORTH, D
对雌性杜父鱼G_1、Sb、Ser两对第三染色体基因间的重组率进行了选择。黑腹菌在开始选择之前，将这些基因置于主要来源于自然群体（IV）的遗传背景上。16个品系中的一个显示出对选择的显著响应; Gl和Sb之间的重组从13%增加到22%。没有证据表明Gl-Sb高重组原种与对照之间在F1中存在定向优势，但存在小的（约0.01）定向优势。1.5%），但存在显著的倒数差异。回交实验表明，这是由于核基因型的祖母效应，可能是由3号染色体上的基因控制的。这些实验还表明，2号和3号染色体对原种之间的差异有显著影响; X染色体效应有提示性但非决定性的证据。唾液染色体研究排除了细胞学检测到的染色体重排在这些影响中的任何作用。
Artifical selection was practised for increased and decreased rates of recombination between 2 pairs of 3rd chromosome genes G1, Sb, Ser, in female D. melanogaster. These genes were placed on a genetic background derived largely from a natural population (IV), prior to the start of selection. One line out of 16 showed a significant response to selection; recombination between Gl and Sb was increased from 13% to 22%. There was no evidence for directional dominance in the F1 betweeen the Gl-Sb high recombination stock and the unselected control, but there was a small (.apprxeq. 1.5%) but significant reciprocal difference. Backcross experiment showed that this was due to a grandmaternal effect of the nuclear genotype, probably controlled by genes on chromosome 3. These experiments also demonstrated that chromosomes 2 and 3 contributed significantly to difference between the stocks; there was suggestive but not conclusive evidence for an X chromosome effect. Salivary chromosome studies ruled out any role of cytologically detectable chromosome rearrangements in these effects.