Palladium-catalyzed selective synthesis of 2-allyltetrazoles
Palladium-catalyzed selective synthesis of 2-allyltetrazoles
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DOI：
10.1021/jo026147l
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发表时间：
2002-10-18
影响因子：
3.6
通讯作者：
Yamamoto, Y
中科院分区：
文献类型：
--
作者：
Kamijo, S;Jin, T;Yamamoto, Y
在Pd-2（dba）（3）·CHCl 3（2.5mol%）和三（2-呋喃基）膦（10mol%）催化下，氰基化合物、烯丙基甲基碳酸酯和三甲基硅叠氮的三组分偶联反应（TCC）得到了各种2-烯丙基四唑，产率较高。一个π-烯丙基钯叠氮配合物提出作为一个关键的中间体在TCC反应。
The palladium-catalyzed three-component coupling (TCC) reaction of cyano compounds, allyl methyl carbonate, and trimethylsilyl azide under a catalytic amount of Pd-2(dba)(3).CHCl3 (2.5 mol %) and tri(2-furyl)phosphine (10 mol %) gave various kinds of 2-allyltetrazoles in good to excellent yields. A pi-allylpalladium azide complex is proposed as a key intermediate in the TCC reaction.