Venous glucose and arterial lactate as biochemical predictors of mortality in clinically severely injured trauma patients - A comparison with ISS and TRISS
Venous glucose and arterial lactate as biochemical predictors of mortality in clinically severely injured trauma patients - A comparison with ISS and TRISS
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DOI：
10.1016/j.injury.2008.07.032
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发表时间：
2009-01-01
影响因子：
2.5
通讯作者：
Hill, Andrew G.
中科院分区：
文献类型：
--
作者：
Sammour, Tarik;Kahokehr, Arman;Hill, Andrew G.
背景：早期评估损伤严重程度在创伤中很重要。创伤评分是事后计算的，对审计和研究有用，但不适用于紧急临床环境。葡萄糖代谢在创伤中发生改变，我们假设葡萄糖和乳酸水平的改变可能是死亡率的早期预测因子。方法：回顾2000年5月至2006年9月创伤登记数据，确定1197例创伤小组呼出的患者。收集的数据包括创伤评分、到达时静脉葡萄糖（gluc）和动脉乳酸（lact）。用ROC曲线比较各变量的预测价值。结果：葡萄糖浓度为11.0 mmol/L的患者死亡率为13.4%，而葡萄糖浓度为2.0 mmol/L的患者死亡率为1.8%，而乳酸浓度为2.7%
Background: Early assessment of injury severity is important in trauma. Trauma scores are calculated after the fact and are useful for audit and research, but not in the emergency clinical setting. Glucose metabolism is altered in trauma, and we hypothesised that alterations in glucose and lactate levels would be an early predictor of mortality.Methods: Review of trauma registry data identified 1197 patients between May 2000 and September 2006 who had a trauma-team call out. Data collected included trauma scores, venous glucose (gluc), and arterial lactate (lact) on arrival. The predictive value of these variables was compared by ROC curves.Results: The mortality rate for patients with gluc >11.0 mmol/L was 13.4% compared to 1.8% in those with gluc 2.0 mmol/L died, versus 2.7% with lact