Comparison of a new multidose powder inhaler (Diskus/Accuhaler) and the Turbuhaler regarding preference and ease of use.
Comparison of a new multidose powder inhaler (Diskus/Accuhaler) and the Turbuhaler regarding preference and ease of use.
复制标题
新型多剂量粉末吸入器 (Diskus/Accuhaler) 和 Turbuhaler 在偏好和易用性方面的比较。
DOI：
10.3109/02770909809068202
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发表时间：
1998
期刊：
影响因子：
--
通讯作者：
Angelique M. Schildkamp
中科院分区：
文献类型：
--
作者：
J. Palen;J. J. Klein;Angelique M. Schildkamp
许多哮喘或慢性阻塞性肺病（COPD）患者无法有效地使用吸入器。一些研究表明，吸入器的具体设计特点对故障率有很大影响，这清楚地表明需要开发更“万无一失”的吸入器。本研究比较了Admus/Accuhaler（DA）与都保（TH）的易用性和患者偏好。50例15岁及以上的哮喘或COPD患者被纳入DA与TH关于患者偏好和易用性的随机交叉比较。所有人都必须对DA和TH一无所知，但目前必须使用另一种装置吸入药物。使用吸入器特定检查表评估吸入技术，患者必须说明在各个方面对DA或TH的偏好以及总体偏好。使用DA的46例患者（92%）在基本吸入操作方面没有错误，而使用TH的37例患者（74%）（p = 0.023）。这种差异完全是由于没有正确装载TH造成的。当患者被问及他们更喜欢哪种吸入器时，17人想要DA，25人想要TH，8人没有说明偏好。差异无显著性。TH优于DA的大小和可用剂量的数量有关的因素。DA的计数机制优于TH。似乎患者对TH有明显的偏好，尽管没有统计学意义，但使用DA的患者较少犯关键错误。
Many patients with asthma or chronic obstructive pulmonary disease (COPD) use their inhaler ineffectively. Several studies revealed that inhaler-specific design features contributed significantly to the failure rate, which clearly demonstrates the need for developing more "foolproof" inhalers. This study compared ease of use and patient preference of the Diskus/Accuhaler (DA) with the Turbuhaler (TH). Fifty patients with asthma or COPD aged 15 years and older were included in a randomized, crossover comparison of DA with TH regarding patient preference and ease of use. All had to be naïve to DA and TH, but currently had to be using inhaled medication with another device. Inhalation technique was assessed using inhaler-specific checklists and patients had to state a preference for DA or TH regarding various aspects, as well as overall preference. With DA 46 patients (92%) made no errors regarding essential inhalation maneuvers, compared to 37 patients (74%) using TH (p = 0.023). This difference is exclusively caused by not loading the TH properly. When patients were asked which inhaler they would prefer, 17 wanted the DA, 25 the TH, and 8 did not state a preference. The difference was not significant. TH was favored over DA regarding factors related to size and the number of available dosages. The counting mechanism of the DA was preferred over the TH. It seems that patients have a clear, although not statistically significant, preference for TH, but with the DA fewer patients make crucial errors.
评估成人哮喘患者使用计量吸入器的情况。
DOI：
10.3109/02770908909073253
发表时间：
1989
期刊：
The Journal of asthma : official journal of the Association for the Care of Asthma
影响因子：
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作者：
Manzella,BA;Brooks,CM;RichardsJr,JM;Windsor,RA;Soong,S;Bailey,WC
通讯作者：
Bailey,WC