Enhancement of Daptomycin Production by the Method of Combining Ribosome Engineering and Genome Shuffling in Streptomyces roseosporus
Enhancement of Daptomycin Production by the Method of Combining Ribosome Engineering and Genome Shuffling in Streptomyces roseosporus
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核糖体工程与基因组改组相结合提高玫瑰孢链霉菌达托霉素产量
DOI:
10.1134/s0003683818060169
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发表时间:
2018-11
影响因子:
0.8
通讯作者:
Guanghai Yu
中科院分区:
文献类型:
--
作者:
Guanghai Yu
Daptomycin, produced by Streptomyces roseosporus is a novel calcium-dependent cyclic lipopeptide used as antibiotic in treatment of human infections caused by Gram-positive bacteria. However, the yield of daptomycin needs to be further enhanced to reduce
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