Statistical modelling of the determinants of historical exposure to bitumen and polycyclic aromatic hydrocarbons among paving workers

Statistical modelling of the determinants of historical exposure to bitumen and polycyclic aromatic hydrocarbons among paving workers
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DOI:
10.1016/s0003-4878(99)00101-5
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发表时间:
2000-01-01
影响因子:
--
通讯作者:
Boffetta, P
Boffetta, P
中科院分区:
医学3区
文献类型:
--
作者:
Burstyn, I;Kromhout, H;Boffetta, P

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简介:已构建工业卫生数据库,用于沥青工人癌症风险研究中的暴露评估。目的:创建摊铺工人中沥青和多环芳烃 (PAH) 暴露强度的模型。方法:收集来自 8 个国家的摊铺工人 (N = 1581) 的个人暴露测量值。研究了暴露测量之间的相关模式,并使用统计模型确定了影响暴露的因素。结果:可吸入粉尘似乎是沥青烟雾暴露的良好替代指标。沥青烟雾和蒸气水平不相关。苯并(a)芘水平似乎是多环芳烃暴露的良好指标。过去 20 年来,所有风险敞口均稳步下降。胶泥铺设、重新摊铺、表面修整、油砾石摊铺和沥青温度是沥青暴露的重要决定因素。煤焦油的使用决定了 PAH 暴露水平。讨论:沥青烟雾、蒸气和 PAH 具有不同的暴露决定因素。对于摊铺工人来说,可以根据时间段和生产特点评估暴露强度。 (C) 2000 年英国职业卫生学会,Elsevier Science Ltd 出版。保留所有权利。
Introduction: An industrial hygiene database has been constructed for the exposure assessment in a study of cancer risk among asphalt workers.Aim: To create models of bitumen and polycyclic aromatic hydrocarbons (PAH) exposure intensity among paving workers.Methods: Individual exposure measurements from pavers (N = 1581) were collected from 8 countries. Correlation patterns between exposure measures were examined and factors affecting exposure were identified using statistical modelling.Results: Inhalable dust appeared to be a good proxy of bitumen fume exposure. Bitumen fume and vapour levels were not correlated. Benzo(a)pyrene level appeared to be a good indicator of PAH exposure. All exposures steadily declined over the last 20 years. Mastic laying, re-paving, surface dressing, oil gravel paving and asphalt temperature were significant determinants of bitumen exposure. Coal tar use dictated PAH exposure levels.Discussion: Bitumen fume, vapour and PAH have different determinants of exposure. For paving workers, exposure intensity can be assessed on the basis of time period and production characteristics. (C) 2000 British Occupational Hygiene Society, Published by Elsevier Science Ltd. All rights reserved.