Prevalence and Antimicrobial Resistance of Campylobacter Isolates from Humans and Chickens in Bahir Dar, Ethiopia
Prevalence and Antimicrobial Resistance of Campylobacter Isolates from Humans and Chickens in Bahir Dar, Ethiopia
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DOI：
10.1089/fpd.2009.0433
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发表时间：
2010-06-01
影响因子：
2.8
通讯作者：
Mihret, Adane
中科院分区：
文献类型：
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作者：
Ewnetu, Desalegne;Mihret, Adane
本研究分析了埃塞俄比亚巴希尔达尔地区鸡源和人源空肠弯曲菌和结肠弯曲菌的分离和耐药性。2007年10月至2008年4月期间，对210份人类和220份鸡样本进行了分析。分离出17种人和160种鸡弯曲杆菌。嗜热弯曲杆菌的总体患病率在人类和鸡中分别为8%和72.7%。在人类中，94.1%的分离株是C。空肠为C.杆菌C.空肠是所有类型患者中嗜热弯曲菌的优势种。鸡嗜热弯曲菌中92.5%为C.空肠和空肠的C.杆菌16株C.人空肠弯曲菌对氨苄西林、环丙沙星、红霉素、萘啶酸、链霉素和四环素的耐药率分别为18.8%、12.5%、12.5%、18.8%、25%和22.2%;对氨苄青霉素、红霉素、链霉素和四环素的耐药率分别为17.5%、14.9%、12.2%和13.5%。在12株C.鸡源大肠杆菌对氨苄青霉素、链霉素和四环素的耐药率分别为16.6%、8.3%和16.6%。总体抗性水平在C. jejuni和C.人和家禽的大肠杆菌分离株。检测到常用抗菌剂的耐药分离株可能会限制治疗选择，从而对人类和鸡造成威胁。
In this study, the isolation and antimicrobial resistance of Campylobacter jejuni and Campylobacter coli strains from chickens and humans in Bahir Dar, Ethiopia, were analyzed. Two hundred and ten human and 220 chicken samples were analyzed between October 2007 and April 2008. Seventeen human and 160 chicken Campylobacter species were isolated. The overall prevalence of thermophilic campylobacters was 8% and 72.7% in humans and chickens, respectively. In humans, 94.1% of the isolates were C. jejuni and 5.9% were C. coli. C. jejuni was a predominant species of thermophilic campylobacters in all categories of patients. In chicken, 92.5% of thermophilic campylobacters isolated were C. jejuni and 7.5% were C. coli. Among the 16 isolates of C. jejuni in humans, 18.8%, 12.5%, 12.5%, 18.8%, 25%, and 22.2% were resistant to ampicillin, ciprofloxacin, erythromycin, nalidixic acid, streptomycin, and tetracycline, respectively, whereas among the 148 C. jejuni isolates from chicken, 17.5%, 14.9%, 12.2%, and 13.5% were resistant to ampicillin, erythromycin, streptomycin, and tetracycline, respectively. Among the 12 isolates of C. coli in chicken, 16.6%, 8.3%, and 16.6% were resistant to ampicillin, streptomycin, and tetracycline, respectively. The overall level of resistance was not significantly different in C. jejuni and C. coli isolates of both humans and poultry. The detection of resistant isolates for commonly used antimicrobials may cause a threat to humans and chickens by limiting therapeutic options.